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Published on: September 5, 2017
Disseminated tuberculosis in an immunocompetent patient
Filippo Mearelli1, Ismet Burekovic, Michela Zanetti
1Internal Medicine Division Cattinara Hospital, Strada di Fiume 447, Trieste, Italy. filippome@libero.it
Miliary tuberculosis can lead to rare tuberculous mycotic aneurysms, even without typical risk factors. Early diagnosis and treatment are crucial for managing this serious complication of Mycobacterium tuberculosis infection.
Area of Science:
- Infectious Diseases
- Cardiovascular Medicine
- Radiology
Background:
- Miliary tuberculosis is a disseminated form of Mycobacterium tuberculosis infection.
- Aortic aneurysms are rare complications of tuberculosis, often linked to contiguous spread.
- Mycotic aneurysms typically result from bacterial seeding of the aortic wall.
Observation:
- A case of tuberculous mycotic aneurysm in the aorta is presented in a patient with miliary tuberculosis.
- The patient had no cellular immunodeficiency or other common risk factors for infection.
- Mycobacterium tuberculosis was eventually identified in lung, lymph nodes, and gastric lavage.
Findings:
- The patient received anti-tubercular therapy and endovascular stenting.
- Diagnosis was confirmed despite initial lack of microbiological evidence.
- This case highlights an unusual presentation of disseminated tuberculosis.
Implications:
- Clinicians should consider Mycobacterium tuberculosis as a cause of mycotic abdominal aortic aneurysms, even with negative cultures.
- The presence of a contiguous tubercular focus should raise suspicion for aortic involvement.
- Prompt diagnosis and management are vital for improving outcomes in tuberculous mycotic aneurysms.
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