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Related Concept Videos

Diabetic Neuropathy01:22

Diabetic Neuropathy

DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses, temperature changes,...
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...

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Updated: May 9, 2026

Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy
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Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy

Published on: July 14, 2023

Peripheral neuropathy in the elderly.

Miki Suzuki1

  • 1Department of Neurology, Tokyo Women's Medical University, Tokyo, Japan.

Handbook of Clinical Neurology
|August 13, 2013
PubMed
Summary

Peripheral neuropathy significantly impacts elderly disability. Identifying and treating treatable causes like diabetes and inflammatory conditions is crucial for this growing population.

Area of Science:

  • Geriatrics
  • Neurology
  • Internal Medicine

Background:

  • Peripheral neuropathy is a major cause of disability in the elderly.
  • The aging population (over 60) constitutes up to 20% in industrialized nations.
  • Neuropathies are common in older adults, with specific types being more prevalent in this demographic.

Purpose of the Study:

  • To highlight the significance of peripheral neuropathy in elderly disability.
  • To emphasize the prevalence of potentially treatable neuropathies in older individuals.
  • To underscore the necessity of diagnosing and managing neuropathies in the elderly population.

Main Methods:

  • Review of existing literature on peripheral neuropathy in the elderly.
  • Analysis of common causes of neuropathy in older adults.
Keywords:
chronic inflammatory demyelinating polyneuropathyelderly patientsmonoclonal gammopathypathologyvasculitic neuropathy

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Evaluating the Function of the Foot Core System in the Elderly
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Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy
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Evaluating the Function of the Foot Core System in the Elderly
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  • Discussion of diagnostic and therapeutic considerations.

    • Main Results:

    • Potentially treatable neuropathies are as common in the elderly as in younger patients.
    • Neuropathies linked to diabetes, malignancy, and monoclonal gammopathies are particularly frequent in older individuals.
    • Identifying the etiology of neuropathy is key for effective management.

    Conclusions:

    • Peripheral neuropathy presents a significant challenge for elderly disability.
    • Early identification and treatment of underlying causes are essential for improving outcomes in older patients.
    • A comprehensive approach to diagnosing and managing neuropathies in the elderly is warranted.