Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Physiologic amputation for acute pedal sepsis.

T J Bunt1

  • 1Division of Vascular Surgery, Maricopa Medical Center, Phoenix, Arizona 85010.

The American Surgeon
|September 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The epistle according to T. J.

Current surgery·2005
Same author

Vascular graft infections: an update.

Cardiovascular surgery (London, England)·2001
Same author

Infection of a chronically implanted iliac artery stent.

Annals of vascular surgery·1997
Same author

Cost-effective evaluation and treatment for carotid disease.

Archives of surgery (Chicago, Ill. : 1960)·1997
Same author

Superior patency of perforating antecubital vein arteriovenous fistulae for hemodialysis.

Annals of vascular surgery·1997
Same author

Complications of iliac artery stent deployment.

Journal of vascular surgery·1996
Same journal

Complete Response of Merkel Cell Carcinoma to Immunotherapy and Single-Fraction Radiotherapy Following Severe COVID-19 Infection: A Case Report and Review of Immune Mechanism.

The American surgeon·2026
Same journal

Perioperative Acute Myocardial Infarction in Non-Cardiac Operations: A National Analysis.

The American surgeon·2026
Same journal

Outcomes of Completion Cholecystectomy: Association With Patient Comorbidity in a National Database.

The American surgeon·2026
Same journal

Building the Conversation: Editorial Stewardship in Contemporary Surgical Publishing.

The American surgeon·2026
Same journal

Musculoskeletal Pain in Surgeons on Operating Days.

The American surgeon·2026
Same journal

Splenectomy During Cytoreductive Surgery: Marker of Surgical Burden or Independent Predictor of Morbidity?

The American surgeon·2026
See all related articles

Managing pedal sepsis with lower extremity amputation can be life-threatening. This study shows physiologic amputation and hemodynamic monitoring significantly reduce mortality in high-risk patients with acute pedal sepsis.

Area of Science:

  • Vascular Surgery
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Pedal sepsis often necessitates lower extremity amputation, carrying significant mortality risks.
  • Traditional management options include one-stage emergency, two-stage guillotine, or physiologic amputation.
  • High mortality rates (10-40%) are often associated with emergency amputation strategies.

Purpose of the Study:

  • To evaluate the efficacy of a management algorithm for pedal sepsis requiring lower extremity amputation.
  • To assess the outcomes of physiologic amputation combined with intensive hemodynamic monitoring in high-risk patients.
  • To present a derived management algorithm for acute pedal sepsis.

Main Methods:

  • Retrospective analysis of 465 lower-extremity amputations performed over seven years for vascular insufficiency.

Related Experiment Videos

  • Specific focus on 116 patients with acute pedal sepsis managed with physiologic amputation and hemodynamic monitoring.
  • Calculation of overall 30-day operative mortalities for below-knee and above-knee amputations.

    • Main Results:

    • Overall 30-day mortality was 0.5% for below-knee and 2.7% for above-knee amputations.
    • In the high-risk group with acute pedal sepsis, mortality was 5.1% using physiologic amputation and monitoring.
    • This approach demonstrated a significantly lower mortality compared to historical emergency amputation data.

    Conclusions:

    • A structured management algorithm incorporating physiologic amputation and hemodynamic monitoring is effective for pedal sepsis.
    • This strategy can substantially reduce operative mortality in patients with acute pedal sepsis and medical comorbidities.
    • The derived algorithm offers a safer approach to managing complex lower extremity infections.