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Updated: May 9, 2026

A Stable Phantom Material for Optical and Acoustic Imaging
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A Stable Phantom Material for Optical and Acoustic Imaging

Published on: June 16, 2023

Polyacrylamide phantom for self-actuating needle-tissue interaction studies.

Naresh V Datla1, Bardia Konh1, Joe J Y Koo1

  • 1Department of Mechanical Engineering, Temple University, 1947 North 12th Street, Philadelphia, PA 19122, United States.

Medical Engineering & Physics
|August 13, 2013
PubMed
Summary

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This summary is machine-generated.

A novel polyacrylamide gel phantom mimics prostate tissue properties for testing self-actuating needles. This material accurately replicates thermal damage, aiding in the development of precise prostate needle insertion technologies.

Area of Science:

  • Biomaterials Engineering
  • Medical Device Development
  • Tissue Mimicry

Background:

  • Self-actuating needles utilize Nitinol actuators for precise prostate placement.
  • Nitinol actuator heating can cause surrounding tissue thermal damage.
  • A reliable phantom material is needed to assess needle feasibility and thermal effects.

Purpose of the Study:

  • To develop a polyacrylamide gel phantom that mimics the mechanical and thermal properties of prostate tissue.
  • To evaluate the phantom's suitability for testing self-actuating needles and their associated thermal damage.
  • To validate the phantom's ability to replicate thermal injury zones.

Main Methods:

  • Polyacrylamide gel formulations were created by adjusting acrylamide monomer and N,N-methylene-bisacrylamide (BIS) cross-linker concentrations.
Keywords:
PhantomPolyacrylamideProstateSelf-actuating needleThermal damage

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  • Bovine serum albumin (BSA) was incorporated to impart thermal sensitivity.
  • Two distinct gel formulations were prepared to match prostate tissue's elastic modulus.
  • Mechanical properties (rupture toughness, needle deflection) and thermal damage zones were characterized.

    • Main Results:

    • The developed polyacrylamide gels successfully mimicked the mechanical properties of prostate tissue.
    • Two phantom formulations exhibited varying rupture toughness and bevel-tip needle deflection.
    • Resistive heating of an embedded Nitinol wire in the phantom resulted in an opaque zone of 0.40mm.
    • This measured opaque zone closely matched the predicted thermal damage zone of 0.43mm.

    Conclusions:

    • The developed polyacrylamide gel serves as a viable phantom material for evaluating self-actuating needles in prostate applications.
    • The phantom accurately replicates both mechanical tissue properties and thermal damage zones caused by needle actuators.
    • This research facilitates the development and feasibility assessment of advanced needle insertion technologies.