Related Experiment Video
Updated: May 9, 2026
06:20
Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma
Published on: January 12, 2024
Isolated primary malignant lymphoma arising from the optic chiasm
Keiji Tsutsumi1, Tetsuyoshi Horiuchi, Tatsuro Aoyama
1Department of Neurosurgery, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan.
Summary
Primary malignant lymphoma rarely affects the anterior visual pathway. This case study details a patient with isolated diffuse large B-cell lymphoma originating in the optic chiasm, presenting with visual disturbances.
Area of Science:
- Ophthalmology
- Neurology
- Oncology
Background:
- Malignant lymphoma rarely originates in the anterior visual pathway.
- Primary tumors of the optic chiasm are uncommon.
Observation:
- A 59-year-old man experienced progressive, painless, bilateral visual disturbance.
- Neurological imaging identified an enhancing mass at the optic chiasm.
Findings:
- Histopathology confirmed diffuse large B-cell lymphoma.
- Systemic examination ruled out disseminated lymphoma.
Implications:
- This case highlights the possibility of isolated primary lymphoma in the anterior visual pathway.
- Early diagnosis and treatment are crucial for visual preservation.
Related Concept Videos
01:16Primary Lymphoid Organs
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
01:15Secondary Lymphoid Organs
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...