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Related Experiment Video

Updated: May 9, 2026

Establishment of an Embryo Implantation Model In Vitro
05:13

Establishment of an Embryo Implantation Model In Vitro

Published on: June 21, 2024

New approaches to embryo selection.

Markus Montag1, Bettina Toth, Thomas Strowitzki

  • 1Department of Gynecological Endocrinology and Fertility Disorders, University of Heidelberg, Voßstr. 9, D-69115 Heidelberg, Germany.

Reproductive Biomedicine Online
|August 13, 2013
PubMed
Summary
This summary is machine-generated.

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Selecting the best embryo for implantation is crucial in assisted reproduction. While morphology is a traditional indicator, combining it with time-lapse imaging offers a more promising approach for identifying viable embryos.

Area of Science:

  • Reproductive biology
  • Embryology
  • Assisted reproductive technology

Background:

  • Embryo selection is critical in assisted reproduction, with morphology traditionally used.
  • Morphology assessment has limitations in identifying the most implantation-competent embryos.
  • Invasive and non-invasive techniques are being explored to improve embryo selection.

Purpose of the Study:

  • To review current and emerging strategies for embryo selection in assisted reproduction.
  • To evaluate the effectiveness of different embryo assessment methods.
  • To identify future directions for optimizing embryo selection.

Main Methods:

  • Review of invasive techniques (genetic screening, omics analysis).
  • Evaluation of non-invasive techniques (metabolomics).
Keywords:
embryo selectionmorphokineticsmorphologynoninvasivetime-lapse imaging

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Last Updated: May 9, 2026

Establishment of an Embryo Implantation Model In Vitro
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Establishment of an Embryo Implantation Model In Vitro

Published on: June 21, 2024

Efficient and Rapid Isolation of Early-stage Embryos from Arabidopsis thaliana Seeds
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  • Analysis of combined morphology and time-lapse imaging (kinetics).

    • Main Results:

    • Morphology alone has statistical limitations for predicting implantation competence.
    • Invasive methods are still under investigation.
    • Metabolomics showed promise in pilot studies but failed in a randomized controlled trial.
    • Time-lapse imaging combined with morphology offers new insights for embryo deselection and identification of high-potential embryos.

    Conclusions:

    • Current embryo selection methods require improvement.
    • Combined evaluation of morphology and developmental kinetics is the most promising strategy.
    • Future strategies will likely involve integrating multiple assessment approaches for enhanced embryo selection.