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Related Concept Videos

Increased Body Temperature01:25

Increased Body Temperature

A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.

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Related Experiment Video

Updated: May 9, 2026

Inducing Targeted Mild Hyperthermia in Murine Tumor Models through Photothermal Conversion of Near-infrared Light by Intratumoral Gold Nanorods
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Carbon nanotubes in hyperthermia therapy.

Ravi Singh1, Suzy V Torti

  • 1Department of Cancer Biology, Wake Forest School of Medicine, Winston Salem, NC 27157, USA.

Advanced Drug Delivery Reviews
|August 13, 2013
PubMed
Summary

Carbon nanotubes offer a novel approach for thermal tumor ablation, enabling simultaneous imaging and therapy. This review explores their use in treating recurrent or resistant cancers, focusing on enhancing treatment selectivity and addressing safety concerns.

Keywords:
Cancer therapyCarbon nanotubesMultiwalled nanotubesPhotothermal therapySingle-walled nanotubes

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Area of Science:

  • Nanomedicine
  • Biotechnology
  • Oncology

Background:

  • Thermal tumor ablation is an emerging cancer treatment modality.
  • Carbon nanotubes (CNTs) are investigated for their potential in combined imaging and therapy.
  • Recurrent or therapy-resistant tumors present a significant clinical challenge.

Purpose of the Study:

  • To review in vivo applications of carbon nanotube-mediated thermal therapy (CNMTT).
  • To examine the rationale for using CNMTT in recurrent or resistant tumors.
  • To discuss strategies for improving CNMTT's localization, selectivity, and safety.

Main Methods:

  • Literature review of in vivo studies on carbon nanotube-mediated thermal therapy.
  • Analysis of research on CNT properties relevant to thermal ablation and imaging.
  • Examination of studies addressing CNT delivery, targeting, toxicity, and long-term fate.

Main Results:

  • CNTs show promise for in vivo thermal tumor ablation with simultaneous imaging capabilities.
  • CNMTT is particularly relevant for treating tumors resistant to conventional therapies.
  • Strategies exist to enhance CNT localization and cancer cell selectivity, though toxicity and fate require further investigation.

Conclusions:

  • Carbon nanotube-mediated thermal therapy presents a promising avenue for challenging cancer cases.
  • Further research is needed to optimize CNT-based therapies for clinical translation, focusing on safety and efficacy.
  • CNMTT offers a potential alternative or adjunct to existing cancer treatment modalities.