Related Experiment Video
Updated: May 8, 2026

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
Published on: May 2, 2025
Metabolic phenotyping of diabetic nephropathy
V-P Mäkinen1, A J Kangas, P Soininen
11] Department of Integrative Biology and Physiology, University of California Los Angeles, Los Angeles, California, USA [2] Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland [3] Folkhälsan Institute of Genetics, Biomedicum Helsinki, Helsinki, Finland.
None:
Diabetic nephropathy is the most serious complication of type 1 diabetes. There is no treatment to protect the kidneys from poorly controlled diabetes, and therefore prevention of the initial metabolic insults is currently the only effective approach to reducing the high mortality related to diabetic nephropathy. Metabolic phenotyping brings us one step closer to understanding the unique set of regulatory perturbations that predispose to kidney injury and paves the way for multiparametric risk assessment.
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