Related Experiment Video

Updated: May 8, 2026

Studying Muscle Transcriptional Dynamics at Single-molecule Scales in Drosophila
10:22

Studying Muscle Transcriptional Dynamics at Single-molecule Scales in Drosophila

Published on: September 8, 2023

Allele-specific detection of single mRNA molecules in situ

Clinton H Hansen1, Alexander van Oudenaarden

  • 1Harvard University Graduate Biophysics Program, Harvard Medical School, Boston, Massachusetts, USA.

Nature Methods
|August 13, 2013
PubMed

More Related Videos

MicroRNA Amplification and Recognition through Locked-nucleic-acid In situ Hybridization as a Novel Detection and Quantification Method09:06

MicroRNA Amplification and Recognition through Locked-nucleic-acid In situ Hybridization as a Novel Detection and Quantification Method

Published on: October 7, 2025

Single Cell Analysis Of Transcriptionally Active Alleles By Single Molecule FISH06:26

Single Cell Analysis Of Transcriptionally Active Alleles By Single Molecule FISH

Published on: September 20, 2020

Related Concept Videos

In-situ Hybridization02:31

In-situ Hybridization

In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
Types of probes and labels
A probe is a complementary strand of DNA or RNA that binds to corresponding nucleotide sequences in a cell. Many...