Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Radioactivity and Nuclear Equations03:18

Radioactivity and Nuclear Equations

Nuclear chemistry is the study of reactions that involve changes in nuclear structure. The nucleus of an atom is composed of protons and, except for hydrogen, neutrons. The number of protons in the nucleus is called the atomic number (Z) of the element, and the sum of the number of protons and the number of neutrons is the mass number (A). Atoms with the same atomic number but different mass numbers are isotopes of the same element.
A nuclide of an element has a specific number of protons and...
Introduction to Actin01:26

Introduction to Actin

Actin is a highly conserved cytoskeletal protein found abundantly in eukaryotic cells. It constitutes 10% weight of the total cellular protein in muscle cells, while in non-muscle cells, it is lower and makes up around 1–5 percent of the total cell protein. Actin found in the unicellular amoebae and complex multicellular animals is around 80% similar, demonstrating their conservation over a billion years of evolution.  Actin coding genes are conserved within species and across different species.
Nuclear Stability03:18

Nuclear Stability

Protons and neutrons, collectively called nucleons, are packed together tightly in a nucleus. With a radius of about 10−15 meters, a nucleus is quite small compared to the radius of the entire atom, which is about 10−10 meters. Nuclei are extremely dense compared to bulk matter, averaging 1.8 × 1014 grams per cubic centimeter. If the earth’s density were equal to the average nuclear density, the earth’s radius would be only about 200 meters.
To hold positively charged protons together in the...
Atomic Nuclei: Nuclear Spin01:08

Atomic Nuclei: Nuclear Spin

All atomic particles possess an intrinsic angular momentum, or 'spin'. Electrons, protons, and neutrons each have a spin value of ½, although protons and neutrons in nuclei may have higher half-integer spins owing to energetic factors.
Atomic nuclei have a net nuclear spin, , which can have an integer or half-integer value. In atomic nuclei, the spins of protons are paired against each other but not with neutrons, and vice versa. Consequently, an even number of protons does not contribute to...
Nuclear Fission02:50

Nuclear Fission

Many heavier elements with smaller binding energies per nucleon can decompose into more stable elements that have intermediate mass numbers and larger binding energies per nucleon—that is, mass numbers and binding energies per nucleon that are closer to the “peak” of the binding energy graph near 56. Sometimes neutrons are also produced. This decomposition of a large nucleus into smaller pieces is called fission. The breaking is rather random with the formation of a large number of different...
Nuclear Transmutation03:20

Nuclear Transmutation

Nuclear transmutation is the conversion of one nuclide into another. It can occur by the radioactive decay of a nucleus, or the reaction of a nucleus with another particle. The first manmade nucleus was produced in Ernest Rutherford’s laboratory in 1919 by a transmutation reaction, the bombardment of one type of nuclei with other nuclei or with neutrons. Rutherford bombarded nitrogen-14 atoms with high-speed α particles from a natural radioactive isotope of radium and observed protons being...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterization of chemotaxis in soybean symbiont <i>Bradyrhizobium diazoefficiens</i>.

Applied and environmental microbiology·2026
Same author

Aeschynomene americana induces terminal bacteroid differentiation in Bradyrhizobium sp. USDA3516, a novel model for dalbergioid-rhizobium symbiosis.

BMC plant biology·2026
Same author

Peer replication : A new tier of science built on reproducibility.

EMBO reports·2026
Same author

A geothermal amoeba sets a new upper temperature limit for eukaryotes.

bioRxiv : the preprint server for biology·2025
Same author

Characterization of chemotaxis in soybean symbiont <i>Bradyrhizobium diazoefficiens</i>.

bioRxiv : the preprint server for biology·2025
Same author

Actin filament assembly driven by distributive polymerases clustered on membrane surfaces.

bioRxiv : the preprint server for biology·2025

Related Experiment Video

Updated: May 8, 2026

Aip1p Dynamics Are Altered by the R256H Mutation in Actin
08:57

Aip1p Dynamics Are Altered by the R256H Mutation in Actin

Published on: July 30, 2014

What we talk about when we talk about nuclear actin.

Brittany J Belin1, R Dyche Mullins

  • 1Cellular and Molecular Pharmacology; University of California; San Francisco, CA USA.

Nucleus (Austin, Tex.)
|August 13, 2013
PubMed
Summary

Nuclear actin forms diverse structures and filaments, playing crucial roles in cell mechanics and gene regulation. This study investigates nuclear actin

Keywords:
cytoskeletonexportin 6importin 9nuclear actinnuclear myosinsoocyte

More Related Videos

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System
09:55

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System

Published on: December 20, 2021

Related Experiment Videos

Last Updated: May 8, 2026

Aip1p Dynamics Are Altered by the R256H Mutation in Actin
08:57

Aip1p Dynamics Are Altered by the R256H Mutation in Actin

Published on: July 30, 2014

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System
09:55

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System

Published on: December 20, 2021

Area of Science:

  • Cell Biology
  • Molecular Biology
  • Biochemistry

Background:

  • Actin filaments in the cytoplasm are essential for cell structure and motility.
  • The function of actin within the cell nucleus remains less understood and debated.
  • Existing literature proposes four main hypotheses regarding nuclear actin's roles.

Purpose of the Study:

  • To critically evaluate existing evidence for nuclear actin functions.
  • To present novel findings on the form and distribution of nuclear actin.
  • To explore the diverse roles of nuclear actin in different cellular contexts.

Main Methods:

  • Comprehensive review and analysis of existing scientific literature on nuclear actin.
  • Development of specific probes for detecting nuclear actin.
  • Microscopic analysis of actin form and distribution in somatic cell nuclei.

Main Results:

  • Four recurring claims regarding nuclear actin's roles were identified and assessed.
  • Novel data on the specific forms and localization of nuclear actin were obtained.
  • Evidence suggests distinct roles for different nuclear actin structures.

Conclusions:

  • Nuclear actin's functions are complex and context-dependent, extending beyond cytoskeletal roles.
  • Specific probes are valuable tools for studying nuclear actin.
  • Further research is needed to elucidate the precise mechanisms of nuclear actin in various physiological settings.