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Common hematological disorders in children
Deepak Bansal1, Sidharth Totadri
1Pediatric Hematology-Oncology Unit, Department of Pediatrics, Advanced Pediatric Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India, deepakbansaldr@gmail.com.
Insights
This article guides primary care physicians on managing common pediatric hematological disorders like anemia and bleeding. It details practical approaches for iron deficiency anemia (IDA) and immune thrombocytopenia (ITP) in children.
Area of Science:
- Pediatric Hematology
- Clinical Practice Guidelines
- Child Health
Background:
- Primary care physicians frequently encounter pediatric hematological disorders.
- Effective management requires practical, evidence-based guidance for first-contact physicians.
Purpose of the Study:
- To offer realistic information for managing common pediatric hematological diseases.
- To illustrate a step-wise approach for investigating anemia and bleeding disorders in children.
Main Methods:
- Review of common pediatric hematological conditions.
- Explanation of iron requirements and management of iron deficiency anemia (IDA) and thalassemia.
- Case scenarios for immune thrombocytopenia (ITP) and hemophilia.
- Emphasis on shared care for acute lymphoblastic leukemia and febrile neutropenia.
Main Results:
- Ferrous sulfate remains the gold standard for IDA due to its bioavailability and cost-effectiveness.
- Delayed umbilical cord clamping is an emerging strategy to improve infant iron stores.
- Risk-based treatment algorithms for febrile neutropenia are presented.
Conclusions:
- Primary care physicians can effectively manage common pediatric hematological disorders with practical guidance.
- Early recognition and appropriate management are crucial for favorable outcomes in pediatric hematology.
- This article serves as a valuable resource for frontline healthcare providers.
Abstract:
It is common for primary care physicians to be faced with children with hematological disorders in everyday practice. The article seeks to provide realistic information for the first-contact physician in handling common hematological diseases in children. Practical step-wise approach to understanding and investigating anemia and bleeding disorders is illustrated. Requirement of iron in normal children and management of iron deficiency anemia (IDA) and thalassemia is explained. The gold standard for IDA continues to be ferrous sulphate which has good bioavailability and is inexpensive. There is emerging concept of delayed clamping of umbilical cord at birth, particularly in regions with widespread IDA, to augment iron stores in infancy. Typical case scenarios of children with immune thrombocytopenia (ITP) and hemophilia are provided to facilitate the understanding of management in day to day practice. The vital role of the medical practitioner in shared care of patients with acute lymphoblastic leukemia and febrile neutropenia is emphasized. A risk based treatment algorithm for febrile neutropenia is provided.
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