Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ventilatory Modes01:14

Ventilatory Modes

Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Mechanical Ventilation I: Indication and Settings01:29

Mechanical Ventilation I: Indication and Settings

Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation (NIPPV)
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned under...
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques01:30

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway interventions are...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Personalizing Chronic Oxygen Prescriptions-Going Beyond P<sub>aO<sub>2</sub></sub> Targeting.

Respiratory care·2025
Same author

Translating Pulmonary Function Test Results into Practical Clinical Interpretations.

Annals of the American Thoracic Society·2025
Same author

It Takes a Village-Evolving Role for Dedicated Teams for COPD Management.

Respiratory care·2025
Same author

A Multidimensional Diagnostic Approach for Chronic Obstructive Pulmonary Disease.

JAMA·2025
Same author

Risk of Atherosclerotic Cardiovascular Disease After Chronic Obstructive Pulmonary Disease Hospitalization among Primary and Secondary Prevention Older Adults.

Journal of the American Heart Association·2025
Same author

Mobile App-Facilitated Collaborative Palliative Care Intervention for Critically Ill Older Adults: A Randomized Clinical Trial.

JAMA internal medicine·2024

Related Experiment Video

Updated: May 8, 2026

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics
12:09

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics

Published on: April 19, 2024

Novel modes of mechanical ventilation.

Mashael Al-Hegelan1, Neil R MacIntyre

  • 1Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.

Seminars in Respiratory and Critical Care Medicine
|August 13, 2013
PubMed
Summary

Positive pressure mechanical ventilation supports gas exchange but does not cure disease. This review assesses novel ventilation approaches against clinical challenges and outcomes.

Area of Science:

  • Critical Care Medicine
  • Respiratory Therapy
  • Biomedical Engineering

Background:

  • Positive pressure mechanical ventilation (PPV) aims to support gas exchange without causing harm.
  • PPV technologies are supportive, not curative, buying time for other treatments.
  • Conventional PPV mimics normal breathing patterns using various support modes and parameters.

Purpose of the Study:

  • To review challenges in mechanical ventilatory support.
  • To assess novel or unconventional PPV approaches introduced in the last two decades.
  • To evaluate these novel approaches based on their ability to address clinical challenges and improve outcomes.

Main Methods:

  • Literature review focusing on mechanical ventilatory support.
  • Analysis of conventional positive pressure ventilation strategies.

More Related Videos

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats
08:22

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats

Published on: September 19, 2025

Mechanical Ventilation Boot Camp Curriculum
07:36

Mechanical Ventilation Boot Camp Curriculum

Published on: March 12, 2018

Related Experiment Videos

Last Updated: May 8, 2026

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics
12:09

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics

Published on: April 19, 2024

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats
08:22

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats

Published on: September 19, 2025

Mechanical Ventilation Boot Camp Curriculum
07:36

Mechanical Ventilation Boot Camp Curriculum

Published on: March 12, 2018

  • Assessment of novel ventilatory approaches introduced over the past 20 years.

    • Main Results:

    • Conventional PPV utilizes assist/control modes, set flow/pressure delivery, and volume/time/flow cycling.
    • Novel PPV approaches have emerged to address limitations of conventional methods.
    • The value of novel approaches is contingent on demonstrating improved clinical outcomes.

    Conclusions:

    • Mechanical ventilators are crucial support tools, not cures for respiratory diseases.
    • Novel ventilation strategies must be rigorously evaluated for clinical efficacy and patient benefit.
    • Future research should focus on developing and validating advanced ventilatory support systems.