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Insertion sequence IS18 mediates overexpression of blaOXA-257 in a carbapenem-resistant Acinetobacter bereziniae

Esther Zander1, Harald Seifert, Paul G Higgins

  • 1Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.

The Journal of Antimicrobial Chemotherapy
|August 13, 2013
PubMed
Abstract

No abstract available in PubMed .

Keywords:
carbapenemaseqRT–PCRrpoB sequencing

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Transposons, or "jumping genes," are small mobile genetic elements (MGEs) that range from 700 to 40,000 base pairs in length. They are found in all organisms and can move within the same chromosome or transfer to different chromosomes. In some cases, transposons can also jump between different host DNA molecules, such as plasmids or viruses, contributing to genetic variability.Barbara McClintock first discovered these mobile genetic elements in the 1940s while studying maize genetics, and she...
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