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Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
Published on: October 18, 2011
Acute late-onset encephalopathy after radiotherapy: an unusual life-threatening complication
Anna Luisa Di Stefano1, Giulia Berzero, Paolo Vitali
1From C. Mondino National Institute of Neurology Foundation (A.L.D., G.B., P.V., C.A.G., M.C., S.B., L.D., E.M.), IRCCS, Pavia, Italy; Neuroscience Consortium (G.B., L.D.), University of Pavia, Monza Policlinico and Pavia Mondino, Italy; Department of Neuro-oncology (F.D.), Hospices Civils de Lyon, Lyon Neuroscience Research Center INSERM U1028/CNRS UMR 5292, Université Claude Bernard Lyon, France; Department of Neuroscience (M.C., S.B.), University of Pavia, Italy; Bone Marrow Transplant Unit (A.A.C.), Department of Hematology Oncology, Foundation IRCCS, Policlinico San Matteo, Pavia, Italy; C.O.U. of Diagnostic Radiology and Interventional Radiology and Neuroradiology (A. Simoncelli), IRCCS Policlinico S. Matteo Foundation, Pavia, Italy; Department of Neurology (M.C.B., B.G.), Ospedale Ca' Foncello, Treviso, Italy; Neuro-oncology Unit (P.G., A. Silvani), Neurological Institute C. Besta, Milan, Italy; and SC Neurologia (A. Salmaggi), Ospedale A. Manzoni, Lecco, Italy.
Abstract:
Unusual late-onset complications of brain irradiation, characterized by reversible neurologic focal signs, seizures, and MRI alterations, have recently been reported and classified as stroke-like migraine attacks after radiation therapy (SMART)(1) and peri-ictal pseudoprogression (PIPG).(2.)
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