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[MKCh-25 ball prosthesis in correction of isolated defect of the mitral valve]
Insights
Mitral valve replacement using the MK4-25 ball prosthesis showed a 6% operative mortality. Long-term survival was significantly better for patients operated on in earlier functional classes, highlighting the benefits of timely intervention for mitral valvular disease.
Area of Science:
- Cardiology
- Cardiac Surgery
- Biomedical Engineering
Background:
- Mitral valvular disease poses significant health risks.
- Ball prostheses are used for mitral valve replacement.
- Understanding long-term outcomes is crucial for patient management.
Purpose of the Study:
- To analyze the immediate and late-term results of mitral valve replacement using the MK4-25 ball prosthesis.
- To evaluate the survival rates and functional outcomes in patients with mitral valvular disease.
Main Methods:
- Retrospective analysis of 605 patients undergoing mitral valve replacement with a MK4-25 ball prosthesis.
- Follow-up periods ranging from 6 months to 17 years for late-term results.
- Assessment of operative lethality and long-term survival based on pre-operative functional class.
Main Results:
- Operative lethality for the final 100 operations was 6%.
- 17-year survival rates were 69% for functional class III and 48.8% for functional class IV patients.
- Late-term survival and functional results were influenced by disease duration and pre-operative circulatory insufficiency.
Conclusions:
- Timely implantation of the MK4-25 ball prosthesis effectively corrects hemodynamic disorders.
- The procedure significantly improves patient survival in mitral valvular disease.
- Early surgical intervention is associated with better long-term outcomes.
Abstract:
The article analyses the immediate and late-term results of mitral valve replacement by a MK4-25 ball prosthesis in 605 patients with mitral valvular disease. Operative lethality for the last 100 operations was 6%. The late-term results of valve replacement were studied in 381 patients in follow-up periods of 6 months to 17 years. 17-year survival was 69% among patients who underwent operation in functional class III and 48.8% among those operated on in class IV. The survival of patients and the late-term functional results depended on the duration of the disease and the degree of circulatory insufficiency before the operation. Timely implantation of a ball prosthesis corrects the hemodynamic disorders satisfactorily and improves the survival of patients.