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Diabetic mastopathy: an uncommon complication of diabetes mellitus

R X Kirby1, D I Mitchell, N P Williams

  • 1Department of Surgery, Radiology, Anaesthesia and Intensive Care, University of the West Indies, Mona, Kingston 7, Jamaica.

Case Reports in Surgery
|August 13, 2013
PubMed

Introduction. Whilst most consequences of diabetes mellitus are well recognized, breast-related complications remain obscure. The term diabetic mastopathy (DMP) attempts to describe the breast-related consequences of diabetes. Methods. We report the clinicopathologic findings in a patient with DMP and review the literature on this uncommon entity. Results. A 33-year-old woman with type 1 diabetes had excision biopsy of a 2 cm breast lump. Histopathologic evaluation revealed classic features of DMP: parenchymal fibrosis; keloid-like hyalinization of interlobular stroma; adipose tissue entrapment; lobular compression; dense chronic inflammatory cell infiltration; and lymphoid follicle formation. Conclusion. Clinicians should be aware of DMP as a differential for breast disease in women with uncontrolled diabetes.

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