Related Experiment Videos
Cardiovascular disease and hip fracture among older inpatients in Beijing, China
1Medical Informatics Center, Peking University, Haidian District, Beijing 100191, China.
Insights
Cardiovascular disease (CVD) significantly increases hip fracture risk in older adults. This association was observed in Chinese inpatients and aligns with European study findings, highlighting a critical link between heart health and bone fragility.
Area of Science:
- Gerontology
- Cardiology
- Epidemiology
Background:
- Cardiovascular disease (CVD) is a major health concern in aging populations.
- Hip fractures represent a significant cause of morbidity and mortality in older adults.
- Understanding the interplay between CVD and hip fracture is crucial for preventative strategies.
Purpose of the Study:
- To investigate the association between cardiovascular disease (CVD) and hip fracture in older Chinese inpatients.
- To determine if hypertensive disease influences the relationship between CVD and hip fracture.
Main Methods:
- Analysis of hospitalization data from 31 tertiary hospitals in Beijing, China (2006-2010).
- Inclusion of 864,408 inpatients aged 55 years and older.
- Identification of hip fractures (ICD-10 codes S72.0, S72.1, S72.2) and CVD comorbidities (ICD-10 codes I00-I99).
Main Results:
- Older inpatients with CVD had a 53% higher occurrence rate of hip fracture compared to those without (RR = 1.53).
- Hip fracture patients were more likely to have hypertensive or cerebrovascular disease (risk 1.34-1.70).
- Hypertensive disease did not alter the association between cerebrovascular disease and hip fracture.
Conclusions:
- Cardiovascular disease is positively associated with hip fracture in older Chinese inpatients.
- The observed associations are comparable to findings from European cohort studies.
- These results underscore the importance of managing CVD to reduce hip fracture risk.
Objectives:
To examine the associations between cardiovascular disease (CVD) and hip fracture and to determine if these associations are attributable to hypertensive disease.
Methods:
Data were obtained from 2006-2010 hospitalization summary reports of 31 tertiary hospitals in Beijing, China. This study included 864,408 inpatients aged ≥55 years. Occurrence rate of hip fracture was based on the first-listed ICD-10 codes (S72.0, S72.1, and S72.2) and of CVD as comorbidities were based on the second- to the eighth-listed ICD-10 codes (I00-I99).
Results:
The occurrence rate of hip fracture is 53% higher among older inpatients with a diagnosis of CVD than those without (RR = 1.53, 95% CI 1.47-1.60). Those with hip fracture were more likely to have hypertensive or cerebrovascular disease, with the risk ranging from 1.34 to 1.70. Compared with those without hip fracture, the occurrence rate of overall CVDs increased by 80%, 83%, and 16% among hip fracture patients aged 55-64, 65-79, and ≥80 years. In addition, hypertensive disease did not modify the association between cerebrovascular disease and hip fracture.
Conclusion:
CVD was positively associated with hip fracture, and the associations observed in this sample of Chinese inpatients were similar to those reported from cohort studies conducted in the European populations.