Related Experiment Video
Updated: May 8, 2026

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
Published on: October 14, 2016
Profile of childhood cancers: a multicentric study
Birendra Nath Roy1, Radheshyam Purkait, Subir Ganguly
1Department of Paediatric Medicine, NRS Medical College, Kolkata 700014.
Insights
Childhood cancer incidence is rising in India. Leukaemia, lymphoma, and retinoblastoma were most common, with variations by age, highlighting the need for a pediatric cancer registry.
Area of Science:
- Pediatric Oncology
- Epidemiology
- Public Health
Background:
- Cancer incidence is increasing in developing nations, particularly in India.
- Childhood cancers have unique genetic and environmental etiological factors.
- Cancer incidence profiles vary geographically and culturally.
Purpose of the Study:
- To analyze the incidence and profile of childhood cancers in West Bengal, India.
- To identify common childhood cancers and their age-specific variations.
- To emphasize the need for a dedicated pediatric cancer registry.
Main Methods:
- Retrospective data collection from three medical college hospitals in West Bengal.
- Data analysis for childhood cancer cases between 2008 and 2011.
- Categorization of cancers by type and age group.
Main Results:
- Leukemia was the most frequent childhood cancer, followed by lymphoma and retinoblastoma.
- Age-specific variations were observed: retinoblastoma, renal tumors, neuroblastoma, and hepatic tumors were more common in children under five.
- Lymphoma, leukemia, bone tumors, and central nervous system tumors were more prevalent in children over five.
Conclusions:
- Childhood cancer profiles exhibit significant age-related variations.
- Effective management requires understanding these diverse patterns.
- A dedicated pediatric cancer registry is crucial for accurate assessment and improved outcomes in India.
Abstract:
The incidence of cancer has been increasing steadily in the developing world including India. Childhood cancers are a special entity with different genetic, environmental factors playing a role in their aetiology. The profiles of cancer incidence reflect the racial, cultural and geographical diversity within populations. This article shows the profile of childhood cancer across three medical college hospitals in the state of West Bengal in India and the data were collected from the period between 2008 and 2011. The results showed leukaemia was the most common cancer affecting children followed by lymphoma and retinoblastoma.The profile of childhood cancers showed wide variation among the age groups. Frequency of retinoblastoma, renal tumours, neuroblastoma and hepatic tumours were higher in children less than five years whereas lymphoma, leukaemia, bone tumours and central nervous system tumours were found more in children above five years. As many of common childhood malignancies are curable there is need to have a dedicated paediatric cancer registry for assessing the magnitude of problem in our country as paediatric cancers show wide variation across centres.
Related Concept Videos
Cancers Originate from Somatic Mutations in a Single Cell
Cancers Originate from Somatic Mutations in a Single Cell
Treatment Resistent Cancers
Treatment Resistant Cancers
Cancer-Critical Genes I: Proto-oncogenes
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Cancer-Critical Genes I: Proto-oncogenes
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...