Related Experiment Video
Updated: May 8, 2026

09:20
Intradermal Inoculation of Mycobacterium avium in the Mouse Ear
Published on: July 3, 2025
Tuberculosis of middle ear and mastoid
Siriporn Limviriyakul1, Sacarin Bunbanjerdsuk, Sarun Prakairungthong
1Otoneurology Unit, Department of Otorhinolaryngology, Faculty of Medicine, Siriraj Hospital, Mahidol University Bangkok, Thailand. sendtojae@gmail.com
Summary
Tuberculosis of the middle ear is rare, often presenting with chronic otorrhea. Early diagnosis through identification of tuberculosis is crucial for effective treatment, which primarily involves medication.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Microbiology
Background:
- Tuberculosis (TB) can affect the middle ear, a rare but significant clinical entity.
- Middle ear tuberculosis presents with diverse clinical manifestations, often mimicking common ear infections.
Observation:
- A retrospective review of six middle ear tuberculosis cases was conducted.
- Chronic otorrhea was the most frequent clinical manifestation.
- Diagnostic methods included histopathology, tissue culture, and PCR.
Findings:
- Middle ear tuberculosis requires a high index of suspicion.
- Accurate identification of Mycobacterium tuberculosis is essential for management.
- Treatment primarily involves medication, with surgery reserved for specific cases.
Implications:
- Enhanced awareness of middle ear tuberculosis is needed among clinicians.
- Multidisciplinary diagnostic approaches improve patient outcomes.
- Further research into optimal treatment strategies is warranted.
Related Concept Videos
Pulmonary Tuberculosis I
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Tonsillitis I: Introduction
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Etiology
Three primary contributing factors have been identified.
