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Updated: May 8, 2026

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
14:04

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria

Published on: May 8, 2013

Prediction of methicillin-resistant Staphylococcus aureus in patients with non-nosocomial pneumonia

Won Jai Jung1, Young Ae Kang, Moo Suk Park

  • 1Division of Pulmonology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea.

BMC Infectious Diseases
|August 14, 2013
PubMed
Abstract

Insights

Identifying risk factors for Methicillin-resistant Staphylococcus aureus (MRSA) pneumonia in non-hospitalized patients is crucial. Previous MRSA infection, high PSI score, and recent IV antibiotics predict MRSA pneumonia risk.

Area of Science:

  • Infectious Diseases
  • Pulmonology
  • Clinical Microbiology

Background:

  • Methicillin-resistant Staphylococcus aureus (MRSA) is a significant pathogen causing both hospital-acquired and community-acquired pneumonia.
  • Risk factors for non-nosocomial MRSA pneumonia remain incompletely defined.
  • This study aimed to identify admission risk factors for non-nosocomial MRSA pneumonia.

Purpose of the Study:

  • To identify clinical characteristics and risk factors associated with non-nosocomial MRSA pneumonia.
  • To differentiate predictors of MRSA versus non-MRSA pneumonia in community-acquired cases.

Main Methods:

  • A retrospective analysis of 943 patients with culture-positive bacterial pneumonia acquired outside the hospital.
  • Comparison of clinical features between MRSA and non-MRSA pneumonia cases.
  • Logistic regression analysis to identify independent risk factors.

Main Results:

  • MRSA pneumonia was identified in 8.2% of patients, with higher mortality (33.3%) compared to non-MRSA pneumonia (21.5%).
  • Independent risk factors for MRSA pneumonia included prior MRSA infection (OR=6.05), PSI score ≥120 (OR=2.40), and recent intravenous antibiotic use (OR=2.23).
  • A single infiltrate on chest radiography was associated with non-MRSA pneumonia (OR=0.55).

Conclusions:

  • Hospitalized patients with non-nosocomial pneumonia and identified risk factors may benefit from empiric anti-MRSA antibiotic therapy.
  • These risk factors can guide the selection of initial empirical antibiotics for community-acquired pneumonia.

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