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Liver involvement in adults with measles
Aurélien Dinh1, Victoire Fleuret, Thomas Hanslik
1Department of Infectious Diseases, Raymond Poincaré Hospital, Versailles, University, Paris Hospitals, 104, Boulevard Raymond Poincaré, 92380 Garches, France.
Summary
Measles in adults is typically not severe, with liver involvement (hepatitis) being a common symptom, not a complication. This finding suggests hepatitis is a usual part of measles infection in adults.
Area of Science:
- Infectious Diseases
- Hepatology
- Epidemiology
Background:
- Measles is a highly contagious viral illness.
- Liver involvement in measles (measles hepatitis) is recognized but its frequency and impact in adults require further elucidation.
Purpose of the Study:
- To determine the frequency and severity of liver involvement in adult patients diagnosed with measles.
- To assess the correlation between hepatitis and disease severity or secondary bacterial infections in adult measles cases.
Main Methods:
- Retrospective analysis of clinical data.
- Inclusion of 80 adult patients with biologically confirmed measles during a French epidemic.
- Evaluation of liver involvement characteristics and correlation with clinical outcomes.
Main Results:
- Measles in the adult cohort was generally not severe.
- Hepatitis occurred in adult measles patients but was not correlated with disease severity.
- No correlation was found between hepatitis and bacterial coinfection.
Conclusions:
- Hepatitis should be considered a common symptom of measles in adults, rather than a complication.
- The presence of hepatitis does not predict a more severe measles course or secondary bacterial infection in adults.
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