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Successful treatment of cerebral venous thrombosis associated with ulcerative colitis

Satoshi Suda1, Ken-ichiro Katsura, Seiji Okubo

  • 1Division of Neurology, Department of Internal Medicine, Nippon Medical School, Tokyo, Japan.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
|August 14, 2013
PubMed

Insights

Cerebral venous thrombosis (CVT) is a rare complication of inflammatory bowel disease. This case study shows that aggressive treatment for ulcerative colitis (UC) remission is vital for managing CVT in UC patients.

Area of Science:

  • Neurology
  • Gastroenterology
  • Hematology

Background:

  • Inflammatory bowel disease (IBD), including ulcerative colitis (UC), is associated with thromboembolic events.
  • Cerebral venous thrombosis (CVT) is a rare but severe complication in IBD patients.

Observation:

  • A 36-year-old Japanese male with ulcerative colitis presented with cerebral venous thrombosis.
  • The patient's CVT was successfully managed with continuous anticoagulant and pulse steroid therapy.

Findings:

  • Aggressive therapy to induce acute remission of ulcerative colitis is crucial for managing associated cerebral venous thrombosis.
  • Early and intensive treatment of UC may prevent or mitigate CVT development.

Implications:

  • This case highlights the importance of considering CVT in IBD patients with neurological symptoms.
  • Prompt and aggressive management of underlying IBD is essential for improving outcomes in CVT patients with UC.
  • Further research into the mechanisms linking UC and CVT is warranted.

Keywords:
Cerebral venous thrombosisanticoagulant therapyheadachesteroidulcerative colitis

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