Omics technologies and the study of human ageing
Related Experiment Video
Updated: May 8, 2026

Measuring Single-Cell Aging with an Imaging-based Biomarker of Chromatin and Epigenetic Aging
Published on: January 30, 2026
Ana M Valdes1, Daniel Glass, Tim D Spector
11] Department of Twin Research and Genetic Epidemiology, Kings College London, London SE1 7EH, UK. [2] Academic Rheumatology, University of Nottingham, Nottingham NG5 1PB, UK.
Abstract:
Normal ageing is associated with diverse physiological changes in all organ systems but the rate and extent of these changes vary markedly among individuals. One aspect of ageing research focuses on the molecular profiling of the changes that occur with increasing age in humans. Such profiling has implications for disease prevention and treatment. New high-throughput 'omics' technologies (such as genomics, metabolomics, metagenomics and transcriptomics) are enabling detailed studies of these molecular changes and are thus revealing information about the biological pathways that change with age.
Related Concept Videos
Mitochondria
Genomics
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
The Effect of Aging on Tissues
Telomeres and Telomerase
Replicative Cell Senescence

