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Updated: May 8, 2026

3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography

3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography

Published on: October 24, 2019

Image quality improvement in optical coherence tomography using Lucy-Richardson deconvolution algorithm.

S A Hojjatoleslami¹, M R N Avanaki, A Gh Podoleanu

¹Research and Development Centre, Kent Institute of Medicine and Health Sciences, University of Kent, Canterbury, UK.

|August 14, 2013

Summary

This summary is machine-generated.

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This study uses solid phantoms to improve optical coherence tomography (OCT) imaging quality. Deconvolution techniques enhance OCT images for better skin and tissue characterization.

Area of Science:

Biomedical optics
Medical imaging technology
Tissue characterization

Background:

Optical coherence tomography (OCT) offers high resolution for skin tissue analysis.
System imperfections limit practical OCT resolution.
Image quality enhancement is crucial for accurate tissue characterization.

Purpose of the Study:

To investigate the use of solid phantoms for estimating the point spread function (PSF) of OCT systems.
To improve OCT image quality through deconvolution.
To demonstrate the effectiveness of the proposed method on various biological and phantom tissues.

Main Methods:

Utilized solid phantoms (e.g., epoxy-resin) to estimate the OCT system's point spread function (PSF).
Applied iterative Lucy-Richardson deconvolution algorithm to OCT images.

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Published on: October 24, 2019

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

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Validated the method on diverse samples including fingertip skin and basaloid larynx/eyelid tissues.

Main Results:

Successful estimation of PSF using solid phantoms.
Significant improvement in OCT image quality after deconvolution.
Demonstrated applicability across different tissue types and phantoms.

Conclusions:

Solid phantoms are effective for PSF estimation in OCT systems.
Lucy-Richardson deconvolution enhances OCT image resolution and clarity.
The developed method improves OCT-based tissue characterization accuracy.