Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Nonlinear Pharmacokinetics: Causes of Nonlinearity

Nonlinear Pharmacokinetics: Causes of Nonlinearity

Nonlinearity in drug pharmacokinetics is caused by various factors influencing how a drug is absorbed, distributed, metabolized, and excreted. Understanding these nonlinear processes is crucial for predicting drug behavior in the body and optimizing drug dosing regimens.
Nonlinear drug absorption can occur when the process is rate-limited by solubility, carrier-mediated transport systems, or saturation of the presystemic gut wall or hepatic metabolism. For instance, high doses of riboflavin...

Parameters Affecting Nonlinear Elimination: Zero-Order Input, First-Order Absorption and Two-Compartment Model

Parameters Affecting Nonlinear Elimination: Zero-Order Input, First-Order Absorption and Two-Compartment Model

Drugs administered through various routes can lead to nonlinear elimination, resulting in complex pharmacokinetic behaviors crucial to understanding efficacious drug dosing.
When a drug is administered through a constant intravenous infusion and eliminated via nonlinear pharmacokinetics, it follows zero-order input. For example, oral drugs undergo first-order absorption upon administration and are eliminated through nonlinear pharmacokinetics.
In the case of subcutaneously administered drugs,...

Linear Approximation in Time Domain

Linear Approximation in Time Domain

Nonlinear systems often require sophisticated approaches for accurate modeling and analysis, with state-space representation being particularly effective. This method is especially useful for systems where variables and parameters vary with time or operating conditions, such as in a simple pendulum or a translational mechanical system with nonlinear springs.
For a simple pendulum with a mass evenly distributed along its length and the center of mass located at half the pendulum's length, the...

Self-Locking Screw

Self-Locking Screw

A square-threaded screw jack is a mechanical device widely used for lifting heavy loads or applying considerable force. One of the key features that can make a screw jack more effective and reliable is its self-locking capability.
A square-threaded screw jack carrying a load is considered self-locking if the screw retains its position even after the moment applied to it is removed.

MOSFET: Enhancement Mode

MOSFET: Enhancement Mode

Enhancement-mode MOSFETs are pivotal components in electronics, distinguished by their capacity to act as highly efficient switches. They are part of the larger family of metal-oxide Semiconductor Field-Effect Transistors (MOSFETs). They are available in two types: p-channel and n-channel, each tailored to specific polarity operations.
In their basic form, enhancement-mode MOSFETs are typically non-conductive when the gate-source voltage (Vgs) is zero. This default 'off' state means no current...

Linear Approximation in Frequency Domain

Linear Approximation in Frequency Domain

Linear systems are characterized by two main properties: superposition and homogeneity. Superposition allows the response to multiple inputs to be the sum of the responses to each individual input. Homogeneity ensures that scaling an input by a scalar results in the response being scaled by the same scalar.
In contrast, nonlinear systems do not inherently possess these properties. However, for small deviations around an operating point, a nonlinear system can often be approximated as linear.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Multiplexed processing of quantum information across an ultrawide optical bandwidth.

Science advances·2026

Same author

X-ray phase measurements by time-energy correlated photon pairs.

Science advances·2025

Same author

Photonic Quantum State Tomography Using Free Electrons.

Physical review letters·2025

Same author

High-energy picosecond pulses with a single spatial mode from a passively mode-locked, broad-area semiconductor laser.

Optics express·2023

Same author

Persistent dynamics in coupled non-degenerate parametric oscillators: pump saturation prevents mode competition.

Optics express·2023

Same author

Passive symmetry breaking of the space-time propagation in cavity dissipative solitons.

Scientific reports·2022

Search research articles

Related Experiment Video

Updated: May 8, 2026

Automation of Mode Locking in a Nonlinear Polarization Rotation Fiber Laser through Output Polarization Measurements

Automation of Mode Locking in a Nonlinear Polarization Rotation Fiber Laser through Output Polarization Measurements

Published on: February 28, 2016

Mode locking with enhanced nonlinearity--a detailed study.

Shai Yefet¹, Avi Pe'er

¹Department of physics and BINA Center of nano-technology, Bar-Ilan university, Ramat-Gan 52900, Israel.

|August 14, 2013

Summary

Researchers tuned Ti:Sapphire laser operation below the continuous-wave threshold, achieving pulsed laser output directly from zero oscillation. This enhanced Kerr nonlinearity tuning offers new possibilities for ultrafast laser generation.

More Related Videos

Measurement of Scattering Nonlinearities from a Single Plasmonic Nanoparticle

Measurement of Scattering Nonlinearities from a Single Plasmonic Nanoparticle

Published on: January 3, 2016

Low-cost Custom Fabrication and Mode-locked Operation of an All-normal-dispersion Femtosecond Fiber Laser for Multiphoton Microscopy

Low-cost Custom Fabrication and Mode-locked Operation of an All-normal-dispersion Femtosecond Fiber Laser for Multiphoton Microscopy

Published on: November 22, 2019

Related Experiment Videos

Last Updated: May 8, 2026

Automation of Mode Locking in a Nonlinear Polarization Rotation Fiber Laser through Output Polarization Measurements

Automation of Mode Locking in a Nonlinear Polarization Rotation Fiber Laser through Output Polarization Measurements

Published on: February 28, 2016

Measurement of Scattering Nonlinearities from a Single Plasmonic Nanoparticle

Measurement of Scattering Nonlinearities from a Single Plasmonic Nanoparticle

Published on: January 3, 2016

Low-cost Custom Fabrication and Mode-locked Operation of an All-normal-dispersion Femtosecond Fiber Laser for Multiphoton Microscopy

Low-cost Custom Fabrication and Mode-locked Operation of an All-normal-dispersion Femtosecond Fiber Laser for Multiphoton Microscopy

Published on: November 22, 2019

Area of Science:

Laser Physics
Nonlinear Optics
Ultrafast Science

Background:

Ti:Sapphire lasers are crucial for ultrafast science.
Mode-locked operation typically requires a threshold above continuous-wave (CW) operation.
Enhanced Kerr nonlinearity offers new control over laser dynamics.

Purpose of the Study:

To investigate mode-locked operation in a Ti:Sapphire laser with enhanced Kerr nonlinearity.
To explore tuning the pulsed operation threshold below the CW threshold.
To understand the transition from CW to pulsed operation under these conditions.

Main Methods:

Experimental investigation of mode-locking dynamics.
Continuous tuning of the pulsed operation threshold.
Qualitative theoretical modeling of the observed phenomena.

Main Results:

The threshold for pulsed operation was continuously tuned down to and below the CW threshold.
Pulsed oscillation was achieved directly from zero CW oscillation.
The evolution of the mode-locking mechanism was experimentally mapped.

Conclusions:

Enhanced Kerr nonlinearity enables novel control over laser threshold dynamics.
It is possible to initiate pulsed laser operation below the conventional CW threshold.
The findings provide insights into fundamental laser physics and open avenues for new laser designs.