Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diphtheria01:28

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Receptor-mediated Endocytosis01:20

Receptor-mediated Endocytosis

Receptor-mediated endocytosis is when bulk amounts of specific molecules are imported into a cell after binding to cell surface receptors. The molecules bound to these receptors are taken into the cell through inward folding of the cell surface membrane, which is eventually pinched off into a vesicle within the cell. Structural proteins, such as clathrin, coat the budding vesicle.
Clathrin-Mediated Endocytosis of LDL
One well-characterized example of receptor-mediated endocytosis is the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Choroidal and Retinal Imaging Findings in Childhood-Onset Mevalonate Kinase Deficiency: An OCT-Based Case-Control Study.

Ocular immunology and inflammation·2026
Same author

Microvascular markers in systemic sclerosis: a comparative OCT-angiography and nailfold videocapillaroscopy study.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same author

Effects of Glaucoma Stage on Optical Coherence Tomography Angiography Parameters in Patients With Primary Open-Angle Glaucoma.

Cureus·2025
Same author

The use of incisional negative pressure wound therapy on high-risk breast cancer mastectomy patients.

Asian journal of surgery·2024
Same author

Management and Clinical Outcomes of Eyes With Posterior Segment Intraocular Foreign Bodies Seen at a Tertiary Referral Center.

Ophthalmic surgery, lasers & imaging retina·2024
Same author

The earthquake disaster in Türkiye: a perspective on newborn evacuation and an ophthalmological approach.

The Turkish journal of pediatrics·2024

Related Experiment Video

Updated: May 8, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Endogenous endophthalmitis caused by diphtheroid bacillus.

Ebru Esen1, Selcuk Sizmaz, Tuğba Incekalan

  • 1Çukurova University, Faculty of Medicine, Department of Ophthalmology , Adana , Turkey.

Ocular Immunology and Inflammation
|August 15, 2013
PubMed
Summary

Diphtheroids can cause severe eye infections like endophthalmitis, especially in diabetic patients. Prompt treatment restored vision in a case of acute endogenous endophthalmitis linked to diphtheroids.

More Related Videos

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

Conjunctival Commensal Isolation and Identification in Mice
07:52

Conjunctival Commensal Isolation and Identification in Mice

Published on: May 1, 2021

Related Experiment Videos

Last Updated: May 8, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

Conjunctival Commensal Isolation and Identification in Mice
07:52

Conjunctival Commensal Isolation and Identification in Mice

Published on: May 1, 2021

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Diphtheroids, once considered nonpathogenic contaminants, are increasingly recognized as potential causes of serious systemic and ocular infections.
  • Patients with underlying medical conditions, such as uncontrolled diabetes mellitus, are particularly vulnerable to severe infections caused by these bacteria.

Observation:

  • A case report detailing a 46-year-old male patient with uncontrolled diabetes mellitus presenting with acute onset endogenous endophthalmitis.
  • Cultures of the anterior chamber fluid sample revealed heavy growth of diphtheroids, indicating a bacterial cause for the endophthalmitis.

Findings:

  • The patient experienced a full recovery with functional vision restored after receiving appropriate treatment for the diphtheroid infection.
  • This case underscores the pathogenic potential of diphtheroids in the context of endogenous endophthalmitis.

Implications:

  • Highlights the critical importance of prompt and accurate diagnosis and management of endogenous endophthalmitis, particularly in immunocompromised or medically complex patients.
  • Emphasizes the need for heightened clinical suspicion and cautious evaluation of patients presenting with similar symptoms, considering the potential for life-threatening conditions.