Immunoresponsive postinfectious autonomic neuropathy.

Area of Science:

• Neurology
• Immunology

Background:

• Autonomic neuropathies can arise post-infection, impacting sympathetic nervous system function.
• Adrenergic failure presents challenges in maintaining blood pressure and circulation, leading to orthostatic intolerance.

Observation:

• A 36-year-old healthy female presented with symptoms suggestive of autonomic dysfunction following an infection.
• Clinical manifestations included significant orthostatic intolerance attributed to adrenergic failure.

Findings:

• The patient received immunomodulating therapy, specifically corticosteroids and immunoglobulin.
• This therapeutic intervention led to substantial clinical symptom resolution and improved autonomic function test results.

Implications:

• Immunomodulating therapies demonstrate efficacy in treating postinfectious autonomic neuropathies.
• Corticosteroids and immunoglobulin offer a viable treatment strategy for adrenergic failure and associated orthostatic intolerance.