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Updated: May 8, 2026
Neonatal Murine Cochlear Explant Technique as an In Vitro Screening Tool in Hearing Research
Published on: June 8, 2017
Epicutaneous patch test--a new diagnostic option to prevent the rejection of silicone-covered cochlear implants in
Gábor Vass1, Attila Torkos, Anita Altmayer
1Department of Otorhinolaryngology and Head and Neck Surgery, University of Szeged, Tisza Lajos krt. 111, H-6725 Szeged, Hungary.
Objectives:
Cochlear implantation (CI) is a revolutionary method for hearing rehabilitation in patients with severe or profound sensorineural hearing loss. One of the surgical complications may be the necrosis of the skin flap above the receiver-stimulator coil, resulting in device extrusion. Our aim was to find the plausible causes of the silicone covered implant rejection.
Patients And Methods:
Authors present four cases of cochlear implant rejection, briefly describe their dermato-surgical solutions and analyse their innovative method - the epicutanoeus patch testing with silicone samples.
Results:
They observed positive skin reaction in three of the four cases.
Conclusion:
Authors analyse the applicability and results of their surgical solutions and the epicutaneous testing in connection with the prevention of skin flap necrosis and rejection of silicone-covered cochlear implants.
