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Meningitis due to Neisseria meningitidis serogroup B in India

Meenakshi Aggarwal1, Vikas Manchanda, B Talukdar

  • 1Departments of Clinical Microbiology and Infectious Diseases Division, Chacha Nehru Bal Chikitsalaya, Raja Ram Kohli Marg, Geeta Colony, Delhi, India.

Indian Pediatrics
|August 15, 2013
PubMed

Insights

Invasive meningococcal disease (IMD) caused by serogroup B is rare in India. This report details the second case of group B meningococcal infection in India, highlighting the need for enhanced surveillance due to ineffective vaccines.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Epidemiology

Background:

  • Invasive meningococcal disease (IMD) presents a severe clinical course with high mortality rates.
  • Neisseria meningitidis serogroup A is the primary cause of IMD in India and other developing nations.
  • Serogroup B meningococcus, common globally, is historically infrequent in India.

Observation:

  • This paper documents the second reported case of group B meningococcal infection in India.
  • The first case was reported two decades prior to this current case.
  • The rarity of serogroup B meningococcal infections in India is notable.

Findings:

  • The study confirms a rare occurrence of Neisseria meningitidis serogroup B in India.
  • This finding contrasts with the predominant serogroup A strains typically seen in the region.
  • The case underscores the potential for underdiagnosis or misdiagnosis of serogroup B strains in India.

Implications:

  • The emergence of serogroup B meningococcal infections necessitates updated public health surveillance in India.
  • Current vaccines are not effective against serogroup B, emphasizing the need for new vaccine development.
  • Enhanced monitoring is crucial for timely detection and management of invasive meningococcal disease caused by less common serogroups.

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