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Myxoid lipoblastoma
Janani Krishnan1, Varun Hathiramani, Meenal Hastak
1Department of Pediatric Surgery, Lilavati Hospital and Research Centre, Mumbai, India. jankrish.doc@gmail.com
Abstract:
A rapidly growing soft tissue mass in the axilla of an infant raises the suspicion of a lipoblastoma or a liposarcoma. Excisional/incisional biopsy is vital in confirming the diagnosis and hence avoiding aggressive extirpation. This case report highlights the role of histopathology and immunohistochemistry as the gold standard in differentiating a lipoblastoma from a liposarcoma. In some cases where the histopathology is inconclusive, genetic rearrangement of the PLAG1 (pleomorphic adenoma gene 1) oncogene on chromosome 8q12 helps in confirming the diagnosis of lipoblastoma.