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[Secondary immunodeficiency in rheumatological diseases]
D Ernst1, R E Schmidt, T Witte
1Klinik für Immunologie und Rheumatologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str.1, 30625, Hannover, Deutschland. ernst.diana@mh-hannover.de
Zeitschrift Fur Rheumatologie
|August 15, 2013
Summary
Immunosuppressive therapies for autoimmune diseases can cause immune deficits. Doctors must understand these risks and implement screening, monitoring, and vaccinations to minimize infection in immunocompromised patients.
Area of Science:
- Immunology
- Pharmacology
- Infectious Diseases
Context:
- Autoimmune and autoinflammatory diseases require immunosuppressive treatment.
- These therapies induce immune deficits, increasing infection risk.
- Clinicians managing these patients need awareness of infection risks.
Purpose:
- To inform doctors about immune deficits caused by immunosuppressive drugs.
- To highlight common infections in immunocompromised patients.
- To emphasize preventive strategies against infections.
Summary:
- Immunosuppressive treatments are vital for autoimmune/autoinflammatory conditions.
- Understanding therapy-induced immune deficits is crucial for prescribers.
- Pretreatment screening, monitoring, and vaccinations mitigate infection risk.
Impact:
- Enhances clinical knowledge for managing immunosuppressed patients.
- Promotes proactive infection prevention strategies.
- Aims to reduce infection-related morbidity and mortality in vulnerable populations.
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