Related Experiment Video
Updated: May 8, 2026

04:57
Clinical Effects of Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment
Published on: April 26, 2024
Pulse-dose radiofrequency for knee osteoartrithis
Salvatore Masala1, Roberto Fiori, Mario Raguso
1Department of Diagnostic and Molecular Imaging, Interventional Radiology and Radiation Therapy, University "Tor Vergata", Viale Oxford 81, 00133, Rome, Italy, salva.masala@tiscali.it.
Cardiovascular and Interventional Radiology
|August 15, 2013
Summary
Pulse-dose radiofrequency (PDRF) effectively reduced chronic knee pain in elderly patients unresponsive to other treatments. This minimally invasive procedure improved quality of life with no reported complications.
Area of Science:
- Orthopedics
- Pain Management
- Minimally Invasive Procedures
Background:
- Knee osteoarthritis (OA) is a significant cause of disability in the elderly population.
- Chronic knee pain often becomes refractory to conservative treatment modalities, necessitating alternative therapeutic options.
Purpose of the Study:
- To evaluate the efficacy of pulse-dose radiofrequency (PDRF) for managing chronic knee pain in patients who have not responded to conservative therapies.
- To assess the long-term effectiveness and safety of PDRF in this patient group.
Main Methods:
- Forty patients with chronic knee pain refractory to conservative treatment underwent PDRF.
- A 20-gauge cannula was inserted into the knee joint space under fluoroscopic guidance, followed by RF needle insertion.
- PDRF was administered using 1,200 pulses at 45 V with a 20-ms duration and a 480-ms silent phase.
Main Results:
- Mean VAS pain scores significantly decreased from 6.8 pre-procedure to 1.8 at 1 week post-PDRF (p < 0.05).
- Pain relief was sustained at 1 year, with mean VAS scores of 2.3 (p < 0.05).
- Western Ontario and McMaster Universities Osteoarthritis Index scores indicated improved quality of life at 6 months and 1 year post-treatment (p < 0.05).
- No complications were reported in any patients.
Conclusions:
- PDRF is an effective and reliable technique for the palliative management of chronic knee pain in patients with knee OA.
- The procedure demonstrates significant pain reduction and functional improvement with a favorable safety profile.

