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Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury
Published on: August 14, 2019
Diffusion magnetic resonance imaging in preterm brain injury
Anand S Pandit1, Gareth Ball, A David Edwards
1Centre for the Developing Brain, Department of Perinatal Imaging, Division of Imaging Sciences and Biomedical Engineering, King's College London, First Floor, South Wing, St Thomas' Hospital, London, UK.
Neuroradiology
|August 15, 2013
Summary
Diffusion-weighted magnetic resonance imaging (d-MRI) effectively detects white matter injury in preterm infants. These findings correlate with neurodevelopmental outcomes, aiding early intervention strategies.
Area of Science:
- Neuroscience
- Medical Imaging
- Developmental Pediatrics
Background:
- Preterm birth can lead to white matter injury and abnormal maturation, contributing to neurodevelopmental disabilities.
- Early detection of white matter maturation abnormalities is crucial for managing preterm infants.
Purpose of the Study:
- To review the basic concepts and analytical methods of diffusion-weighted magnetic resonance imaging (d-MRI).
- To discuss neuroimaging findings of preterm brain injury across different life stages.
- To explore the link between d-MRI measures and neurodevelopmental performance.
Main Methods:
- Literature review using PubMed and Google Scholar searches conducted before March 2013.
Main Results:
- Premature birth impacts cerebral white matter from term-equivalent age through adulthood.
- d-MRI identifies disruptions in white matter development linked to impaired motor, cognitive, and behavioral performance.
Conclusions:
- d-MRI is a valuable tool for assessing white matter injury in preterm infants.
- Advancements in d-MRI offer potential as a biomarker for predicting outcomes and evaluating interventions.
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