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Updated: May 8, 2026

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation
Published on: June 13, 2025
Upper extremity composite tissue allotransplantation imaging
Elizabeth George1, Dimitrios Mitsouras, Kanako K Kumamaru
1Applied Imaging Science Laboratory, Department of Radiology.
Standardized imaging protocols for upper extremity (UE) transplantation are crucial for pre- and post-operative evaluation. Advanced imaging confirms successful bony union and vascular patency, aiding clinical trial assessments.
Area of Science:
- Composite tissue allotransplantation
- Medical imaging
- Orthopedic surgery
Background:
- Upper extremity (UE) transplantation is the most common composite tissue allotransplantation.
- Current pre- and post-transplant evaluation lacks standardized imaging protocols.
Purpose of the Study:
- To highlight imaging protocols and findings for UE allotransplantation.
- To standardize imaging for clinical trials in UE transplantation.
Main Methods:
- Multimodality imaging including radiography, CT, MR, angiography, and ultrasonography.
- Dynamic CT and MR for motor activity assessment.
- Evaluation of image quality for vessels and bones.
Main Results:
- Preoperative imaging revealed skeletal deformities and vascular variations.
- Posttransplant imaging confirmed bony union and vascular anastomoses patency.
- Dynamic imaging showed functional joint range of motion at 8 months.
Conclusions:
- Advanced imaging is vital for surgical planning and monitoring transplant success.
- Standardized protocols are needed for comprehensive assessment in clinical trials.
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