Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

An improved method for localizing electric brain dipoles.

Y Salu1, L G Cohen, D Rose

  • 1Department of Physics and Astronomy, Howard University, Washington DC 20059.

IEEE Transactions on Bio-Medical Engineering
|July 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

GW190521: A Binary Black Hole Merger with a Total Mass of 150  M_{⊙}.

Physical review letters·2020
Same author

Search for Subsolar Mass Ultracompact Binaries in Advanced LIGO's Second Observing Run.

Physical review letters·2019
Same author

Improving patient experiences of mental health inpatient care: a randomised controlled trial.

Psychological medicine·2017
Same author

Coping with stigma and discrimination: evidence from mental health service users in England.

Epidemiology and psychiatric sciences·2017
Same author

What side effects are problematic for patients prescribed antipsychotic medication? The Maudsley Side Effects (MSE) measure for antipsychotic medication.

Psychological medicine·2017
Same author

The effects of fermentation and enzymatic treatment of pea on nutrient digestibility and growth performance of broilers.

Animal : an international journal of animal bioscience·2017

This study introduces an improved method for brain source localization using a three-layer spherical head model and optimal dipoles. The new technique accurately pinpoints electrical dipolar sources in the brain with high precision.

Area of Science:

  • Neuroscience
  • Biophysics
  • Medical Imaging

Background:

  • Electrical dipolar source localization in the brain involves complex modeling of the head and electroencephalogram (EEG) potentials.
  • Existing methods vary in head models, potential calculation formulas, reference electrode treatment, and fitting algorithms.

Purpose of the Study:

  • To present an advanced method for localizing electrical dipolar sources in the brain.
  • To improve upon existing techniques by integrating advanced features and novel improvements.

Main Methods:

  • Utilized a three-layer spherical model to represent the human head.
  • Employed a closed-form formula for calculating scalp potentials, avoiding matrix rotations.
  • Incorporated a least-squares procedure based on optimal dipoles, reducing unknowns from six to three.

Related Experiment Videos

  • Allowed for any surface electrode to be used as a reference.

    • Main Results:

    • The method was validated by localizing five implanted dipolar sources in the human sensorimotor cortex.
    • Calculated source locations showed distances of 0.4 to 2.0 cm from actual locations.
    • Assessed the method's sensitivity to uncertainties in modeling real heads with a three-layer model.

    Conclusions:

    • The developed method offers a precise and robust approach to brain electrical source localization.
    • The technique's accuracy and sensitivity make it a valuable tool for neuroscience research and clinical applications.