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Related Concept Videos

Dialysis01:27

Dialysis

Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Dialysis01:15

Dialysis

Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
Hemodialysis III: Nursing Management01:25

Hemodialysis III: Nursing Management

The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this measurement...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...

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Related Experiment Video

Updated: May 8, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
06:27

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

Dialysis outcomes in those aged ≥65 years.

Robert Walker, Sarah Derrett, John Campbell

    BMC Nephrology
    |August 16, 2013
    PubMed
    Summary

    Elderly dialysis patients in NZ face limited data on quality of life and survival. This study tracks health outcomes for those over 65 on dialysis to improve care decisions.

    Related Experiment Videos

    Last Updated: May 8, 2026

    A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
    06:27

    A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

    Published on: July 20, 2022

    Area of Science:

    • Geriatric Nephrology
    • Patient-Centered Outcomes Research
    • Health Services Research

    Background:

    • Significant increase in elderly (≥65 years) individuals starting dialysis in New Zealand (nearly 400% in a decade).
    • Limited data exists on health-related outcomes and survival for elderly dialysis patients, hindering informed decision-making.

    Purpose of the Study:

    • To conduct the first comprehensive longitudinal survey of health-related quality of life (HRQOL) and patient-centered outcomes in elderly individuals (≥65 years) undergoing or eligible for dialysis.
    • To link HRQOL and patient-centered outcome data with survival data for this demographic.
    • To inform dialysis service delivery and decision-making for patients, families, and clinicians in New Zealand.

    Main Methods:

    • Longitudinal survey design involving yearly structured interviews with participants aged ≥65 years.
    • Linking interview data with co-morbidity, health service use, and laboratory data from health records.
    • Analysis focused on health-related quality of life (HRQOL) and survival outcomes.

    Main Results:

    • N/A - Study is prospective.

    Conclusions:

    • Study results will empower elderly patients and their families to make more informed decisions regarding renal replacement therapy.
    • Healthcare professionals will be better equipped to communicate the impact of dialysis on quality of life and patient outcomes.