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Related Concept Videos

Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Insulin Formulations: Types and Delivery01:27

Insulin Formulations: Types and Delivery

Insulin preparations are categorized by their duration of action into short-acting and long-acting types. Two strategies are used to modify insulin's absorption and pharmacokinetic profile: slowing the absorption post-subcutaneous injection, or altering human insulin's amino acid sequence or protein structure. These changes retain the insulin's ability to bind to the insulin receptor, but alter its behavior in solution or after injection.
Short-acting insulins are divided into rapid-acting...
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...
Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic symptoms in all...
Antipsychotic Drugs: Typical and Atypical Agents01:21

Antipsychotic Drugs: Typical and Atypical Agents

Antipsychotic drugs are classified into first-generation (typical) drugs including phenothiazines; and second-generation (atypical) drugs. Chlorpromazine hydrochloride (Thorazine), a phenothiazine derivative, broadly impacts the central, autonomic, and endocrine systems. This drug, along with typical agents like haloperidol (Haldol), primarily works by antagonizing D2 receptors, thus reducing dopaminergic neurotransmission. However, typical antipsychotics can cause side effects such as sedation...
Antipsychotic Drugs: Therapeutic Uses and Side Effects01:21

Antipsychotic Drugs: Therapeutic Uses and Side Effects

Antipsychotic drugs primarily block dopamine and serotonin receptors and cholinergic, adrenergic, and histaminergic receptors, thereby reducing hallucinations and delusions in conditions like schizophrenia. However, they can trigger unwanted extrapyramidal effects such as dystonias, Parkinson-like symptoms, and tardive dyskinesia.
Despite these side effects, antipsychotics are used therapeutically for various purposes, including managing schizophrenia, preventing nausea and vomiting, curbing...

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Related Experiment Video

Updated: May 8, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

Long-acting injectable antipsychotics: recommendations for clinicians.

Ashok Malla1, Phil Tibbo, Pierre Chue

  • 1Department of Psychiatry, McGill University, Montreal, Quebec. ashok.malla@douglas.mcgill.ca

Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie
|August 16, 2013
PubMed
Summary

Long-acting injectables (LAIs) can improve antipsychotic treatment adherence for psychotic disorders. Recommendations are provided to increase LAI use across all illness phases, addressing clinical challenges and promoting better patient outcomes.

Keywords:
adherenceantipsychoticslong-acting injectionrecommendationsutilization

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Last Updated: May 8, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
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Published on: November 21, 2013

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Area of Science:

  • Psychiatry and Pharmaceutical Sciences

Background:

  • Patient nonadherence significantly limits antipsychotic effectiveness.
  • Long-acting injectable (LAI) formulations offer a strategy to mitigate adherence issues.
  • The adoption of LAIs in Canada is notably lower compared to other countries.

Observation:

  • Qualitative studies and clinical experience reveal challenges hindering LAI utilization.
  • Randomized controlled trials and other studies demonstrate LAI effectiveness.

Findings:

  • Ten recommendations are proposed to address clinical challenges and promote LAI use.
  • Case examples illustrate the varied application of LAIs across patient populations and illness stages.

Implications:

  • LAIs should be considered a viable treatment option for psychotic disorders throughout all phases of illness.
  • Implementing these recommendations can potentially improve treatment adherence and outcomes for patients with psychotic disorders.