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Three novel xanthones from Garcinia paucinervis and their anti-TMV activity
Yu-Ping Wu1, Wei Zhao, Zhen-Yuan Xia
1Yunnan Academy of Tobacco Agricultural Sciences, Yuxi 653100, China.
Molecules (Basel, Switzerland)
|August 16, 2013
Abstract:
Phytochemical investigations of the leaves of Garcinia paucinervis resulted in the isolation of three new xanthones 1-3 and five known analogues 4-8. Structural elucidations of 1-3 were performed by spectral methods such as 1D and 2D (HMQC, HMBC, and ROESY) NMR spectroscopy, in addition to high resolution mass spectrometry. Compounds 1-3 showed anti-TMV activities, with inhibition rates above 20%, especially for 1, which had a lower IC₅₀ value of 21.4 µM.