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Granular cell tumor on perianal region: a case report
Kesici Ugur1, Mataraci Emine, Kesici Sevgi
1Department of General Surgery, Ministry of Health, Akcaabat Hackali Baba State Hospital, Trabzon, Turkey. ugurkesici77@mynet.com
Acta Medica Iranica
|August 16, 2013
Summary
This case report details a rare anal-perianal granular cell tumor (GCT) in a young woman. Histopathology confirmed a benign GCT, emphasizing the need for careful examination of such lesions.
Area of Science:
- Oncology
- Pathology
- Dermatology
Background:
- Granular cell tumor (GCT) is a rare soft tissue neoplasm, typically benign.
- While common in the head and neck, GCTs are exceptionally rare in the anal-perianal region.
Observation:
- A 23-year-old female presented with a palpable perianal mass.
- Physical examination revealed a 0.5-1 cm pedunculated polypoid lesion in the perianal area.
- The lesion was completely excised under local anesthesia.
Findings:
- Histopathological examination confirmed a benign granular cell tumor.
- Immunohistochemical analysis showed positive staining for S-100 and neuron-specific enolase (NSE).
- This represents one of the few documented cases of anal-perianal GCT.
Implications:
- Anal-perianal GCTs, though rare and usually benign, require thorough histopathological evaluation for accurate diagnosis.
- Complete local excision is curative for benign lesions; however, malignant transformation necessitates further investigation for metastasis.
- Close monitoring for recurrence and metastasis is crucial post-treatment due to the poor prognosis of metastatic disease.
