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Pulse granuloma involving Meckel's diverticulum: a case report and literature review

J K Karp1, A Davis, P J Read

  • 1Thomas Jefferson University Hospital, Methodist Division, Philadelphia, PA 19148, USA. julie.karp@jefferson.edu

Pathologica
|August 17, 2013
PubMed

Insights

This study reports the first case of pulse granuloma found in Meckel's diverticulum. This rare condition, a reaction to vegetable matter, was identified through microscopic examination of resected tissue.

Area of Science:

  • Gastroenterology
  • Pathology

Background:

  • Pulse granuloma is a rare, benign condition.
  • It is characterized by hyaline rings and foreign-body giant cells.
  • It is believed to be a reaction to vegetable material.

Observation:

  • A case of pulse granuloma involving Meckel's diverticulum is presented.
  • The patient exhibited abdominal pain and radiological findings suggestive of Meckel's diverticulum.
  • Microscopic analysis of the resected tissue confirmed Meckel's diverticulum with small bowel mucosa.

Findings:

  • Peridiverticular foreign-body giant cells were identified.
  • Hyaline rings and circular structures with calcified basophilic granules were observed.
  • These findings were consistent with pulse granuloma.

Implications:

  • This is the first reported instance of pulse granuloma occurring in Meckel's diverticulum.
  • Accurate diagnosis of pulse granuloma is crucial, especially in unusual locations.
  • Awareness of this entity aids timely diagnosis in previously undescribed sites.

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