Related Experiment Video
Updated: May 8, 2026
07:15
Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
Published on: December 5, 2025
[Therapy with high-flow nasal prongs in preterm infants]
F Ciuffini1, M Colnaghi, A Lavizzari
1NICU, Department of Clinical Sciences and Community Health, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano.
Summary
High flow nasal cannula (HFNC) offers a promising, better-tolerated alternative to traditional non-invasive ventilation for premature infants with respiratory distress. Further research is needed to confirm its effectiveness and safety for widespread clinical use.
Area of Science:
- Neonatal respiratory support
- Pulmonary complications in preterm infants
- Non-invasive ventilation (NIV) strategies
Context:
- Premature infants face high rates of long-term lung issues, often from mechanical ventilation.
- Nasal continuous positive airway pressure (NCPAP) is an NIV method with nasal trauma and intolerance drawbacks.
- High flow nasal cannula (HFNC) is an emerging NIV approach with improved patient tolerance and facial access.
Purpose:
- To review the current evidence on the effectiveness and safety of HFNC in preterm newborns with respiratory distress syndrome (RDS).
Summary:
- HFNC is an NIV mode that may reduce adverse effects compared to traditional ventilation.
- The distending pressure from HFNC is influenced by flow rate, infant size, and air leaks.
- While HFNC shows feasibility as an NIV alternative, its effects on lung mechanics, clinical efficacy, and safety require more investigation.
- Current evidence suggests HFNC is a viable option, but larger randomized trials are necessary to support its use for moderate RDS in preterm infants.
Impact:
- HFNC may improve nursing care, feeding, and bonding due to better facial access.
- This review highlights the potential of HFNC to optimize respiratory support for vulnerable preterm neonates.
- Further research will guide the clinical adoption of HFNC for managing neonatal respiratory distress.
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The human body requires oxygen to function, and when the natural process of respiration is hindered, external devices, including the following, are needed to help deliver this vital gas.
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...