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Related Concept Videos

Chair Conformation of Cyclohexane02:02

Chair Conformation of Cyclohexane

The chair conformation is the most stable form of cyclohexane due to the absence of angle and torsional strain. The absence of angle strain is a result of cyclohexane’s bond angle being very close to the ideal tetrahedral bond angle of 109.5° in its chair conformer. Similarly, the torsional strain is also absent owing to the perfectly staggered arrangement of bonds.
The hydrogen atoms linked to carbons are arranged in two different axial and equatorial orientations to achieve this staggered...
Introduction to force01:25

Introduction to force

Consider water flowing from a nozzle to a turbine vane. As the water hits the turbine vane, it exerts a force that causes it to move along the flow of direction. Force is an impact that changes an object's motion, shape, or orientation. Forces can be caused by physical contact, such as a push or pull, or through non-contact interactions, such as magnetic or gravitational forces. Force is a vector quantity with both magnitude and direction, and is measured in newtons (N) in the SI unit system.
Introduction to Structures01:30

Introduction to Structures

A structure is defined as a system of interconnected members designed to support or transfer forces and successfully withstand the loads acting on them. The internal forces of a structure can be determined by decomposing the structure and analyzing the free-body diagrams of the individual members or of a combination of members. This helps in understanding the structural elements' behavior and ensuring that the structure is stable and can withstand the subjected loads.
There are three main...
Molecular Chaperones and Protein Folding03:00

Molecular Chaperones and Protein Folding

The native conformation of a protein is formed by interactions between the side chains of its constituent amino acids. When the amino acids cannot form these interactions, the protein cannot fold by itself and needs chaperones. Notably, chaperones do not relay any additional information required for the folding of polypeptides; the native conformation of a protein is determined solely by its amino acid sequence. Chaperones catalyze protein folding without being a part of the folded protein.
The...
Molecular Chaperones and Protein Folding03:00

Molecular Chaperones and Protein Folding

The native conformation of a protein is formed by interactions between the side chains of its constituent amino acids. When the amino acids cannot form these interactions, the protein cannot fold by itself and needs chaperones. Notably, chaperones do not relay any additional information required for the folding of polypeptides; the native conformation of a protein is determined solely by its amino acid sequence. Chaperones catalyze protein folding without being a part of the folded protein.
The...
Introduction to the Cytoskeleton01:33

Introduction to the Cytoskeleton

Overview of the Cytoskeleton
The cytoskeleton is a network of protein filaments present within the cell, having three distinct filaments ̶   microfilaments, microtubules, and intermediate filaments. Each has characteristic features that distinguish them, including the dynamics of their assembly and disassembly, mechanical properties, polarity, and the type of molecular motors associated with them. Earlier, they were thought to be present only in eukaryotic cells; however, their homologs were...

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Related Experiment Video

Updated: May 8, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

[Introductory remarks by chairpersons].

Shunichi Kumagai1, Tsutomu Nobori

  • 1The Center for Rheumatic Diseases, Shinko Hospital, Kobe 651-0072, Japan. kumagai@kobe-u.ac.jp

Rinsho Byori. the Japanese Journal of Clinical Pathology
|August 17, 2013
PubMed
Summary

Personalized medicine (PM), driven by pharmacogenomics (PGx), is advancing healthcare. PGx is crucial for optimizing drug selection and dosing in clinical practice.

Area of Science:

  • Genomic Medicine
  • Molecular Diagnostics

Context:

  • Personalized medicine (PM) adoption is growing, particularly in oncology, due to advancements in pharmacogenomics (PGx) and molecular diagnostics.
  • Targeted therapies in oncology benefit from accurate diagnostic tests, facilitating personalized treatment strategies.
  • Wider acceptance of PM is driven by improved benefit/risk assessments and optimized drug selection/dosing methods.

Purpose:

  • To discuss the critical role of pharmacogenomics (PGx) in advancing personalized medicine (PM).
  • To explore the integration of PGx into clinical practice from both basic and clinical research perspectives.

Summary:

  • Personalized medicine (PM) leverages pharmacogenomics (PGx) and molecular diagnostics for tailored healthcare.
  • While oncology leads in PM adoption, broader clinical application is becoming more feasible.

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A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
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  • Optimized drug selection and dosing are key drivers for PM's increasing relevance.

    • Impact:

    • Accelerating the integration of pharmacogenomics into routine clinical practice.
    • Enhancing the benefit/risk profile of drug therapies for individual patients.
    • Transforming healthcare delivery through precision-based medical interventions.