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Updated: May 8, 2026

11:04
A Cell Free Assay to Study Chromatin Decondensation at the End of Mitosis
Published on: December 19, 2015
PREEParing for mitosis
1Institute of Medical Biology, 8A Biomedical Grove, Immunos, Singapore. brian.burke@imb.a-star.edu.sg
Developmental Cell
|August 17, 2013
Abstract:
Reporting in Developmental Cell, Schlaitz et al. (2013) show that endoplasmic reticulum (ER) membrane exclusion from the mitotic spindle is an active process requiring REEP membrane proteins. REEP protein depletion results in ER membrane retention on the spindle and chromosomes, leading to defects in chromosome segregation and nuclear envelope assembly.
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