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Updated: May 8, 2026

MRI and PET in Mouse Models of Myocardial Infarction
Published on: December 19, 2013
[PET/MRI for cardiac imaging. Possibilities and limits].
1Nuklearmedizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, München, Deutschland.
Positron emission tomography/magnetic resonance imaging (PET/MRI) offers a lower radiation dose alternative to PET/computed tomography (CT) in nuclear cardiology. PET/MRI shows promise for specific applications like imaging inflammatory heart conditions and assessing myocardial viability.
Area of Science:
- Nuclear cardiology
- Hybrid imaging modalities
- Radiological techniques
Background:
- Positron emission tomography/magnetic resonance imaging (PET/MRI) is an emerging hybrid imaging technique.
- The established standard in nuclear cardiology is positron emission tomography/computed tomography (PET/CT).
Purpose of the Study:
- To evaluate the performance and clinical utility of PET/MRI in nuclear cardiology.
- To compare PET/MRI with the current standard, PET/CT.
Main Methods:
- Utilizing MRI for morphological correlation instead of CT.
- Generating attenuation maps (μ-maps) from MRI data.
- Comparing PET/MRI data with PET/CT as the reference standard.
Main Results:
- PET/MRI demonstrates good agreement with PET/CT in nuclear cardiology.
- A significant advantage of PET/MRI is the reduced radiation dose to patients compared to PET/CT.
- The workflow for PET/MRI is more complex, and some applications are still experimental.
Conclusions:
- PET/MRI is recommended for younger patients due to lower radiation exposure.
- PET/MRI offers specific advantages in nuclear cardiology, including imaging inflammatory myocardial processes and assessing myocardial viability.
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