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Updated: May 8, 2026

Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting

Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting

Published on: June 21, 2024

Individual differences in chemotherapy-induced anticipatory nausea.

Marcial Rodríguez¹

¹Laboratory of Comparative Psychology, Department of Experimental Psychology, Faculty of Education and Humanities, University of Granada Ceuta, Spain.

Frontiers in Psychology

|August 17, 2013

Summary

Anticipatory Nausea (AN), a chemotherapy side effect, is often linked to Pavlovian conditioning. However, alternative theories suggest these associations may not be essential for AN development in cancer patients.

Keywords:

chemotherapy classical conditioning differences nausea rat

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Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity

Published on: April 26, 2012

Area of Science:

Psychology
Oncology
Neuroscience

Background:

Anticipatory Nausea (AN) is a significant chemotherapy side effect impacting cancer treatment adherence.
AN is commonly understood as a Pavlovian conditioning response to clinical stimuli.
Previous research proposed behavioral interventions based on the Pavlovian model.

Purpose of the Study:

To critically evaluate the Pavlovian conditioning model of Anticipatory Nausea (AN).
To discuss alternative theories and data challenging the necessity of CS-US associations for AN.
To suggest improvements for animal models of AN.

Main Methods:

Review and discussion of existing data on Anticipatory Nausea.
Analysis of criticisms against the Pavlovian conditioning framework for AN.
Exploration of alternative theoretical explanations for AN.

Main Results:

Some studies question whether Pavlovian conditioning (CS-US associations) is necessary or sufficient for AN.
Alternative theories offer different perspectives on the mechanisms underlying AN.
The discussion highlights limitations in current models of AN.

Conclusions:

The Pavlovian model of AN may not fully explain the phenomenon.
Alternative theories warrant further investigation for a comprehensive understanding of AN.
Incorporating individual differences in animal models could enhance AN research.