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Factors associated with feeding difficulties in the very preterm infant
T L Crapnell1, C E Rogers, J J Neil
1Program in Occupational Therapy, Washington University School of Medicine, St. Louis, MO, USA.
Insights
Early hypotonia and lower socioeconomic status are linked to feeding problems in preterm infants. These factors may disrupt oral-motor skill development and highlight the influence of family background on feeding outcomes.
Area of Science:
- Neonatology
- Developmental Pediatrics
- Pediatric Nutrition
Background:
- Preterm infants face increased risks for feeding difficulties.
- Early identification of risk factors is crucial for intervention.
- Feeding problems can impact long-term growth and development.
Purpose of the Study:
- To investigate early medical and family factors associated with later feeding risk in preterm infants.
- To identify predictors of feeding problems at age 2 years in infants born prematurely.
Main Methods:
- Longitudinal study of 136 infants born ≤30 weeks gestation.
- Assessment of medical, social, neurobehavioral, and maternal factors at term equivalent age.
- Feeding outcome assessed at 2 years using the Infant-Toddler Social Emotional Assessment.
Main Results:
- 23% of children experienced feeding problems at age 2 years.
- Feeding problems were significantly associated with early hypotonia (p=0.03) and lower socioeconomic status (p=0.046).
- No significant associations found with early medical factors, neurobehavioral functioning, cerebral structure, or maternal mental health.
Conclusions:
- Early hypotonia may impede oral-motor skill development in preterm infants.
- Lower socioeconomic status underscores the role of family background in feeding difficulties.
- Findings suggest targeted interventions for hypotonia and socioeconomic support may improve feeding outcomes.
Aim:
To investigate early medical and family factors associated with later feeding risk in preterm infants.
Methods:
For this longitudinal study, 136 infants born ≤30 weeks gestation were enrolled. Medical and social background factors were assessed at term equivalent age. Infants underwent magnetic resonance imaging, neurobehavioral evaluation and feeding assessment. Parent involvement in the neonatal intensive care unit was tracked, and maternal mental health was assessed at neonatal intensive care unit discharge. At age 2 years, feeding outcome was assessed using the Eating Subscale of the Infant-Toddler Social Emotional Assessment (n = 80). Associations between feeding problems at age 2 years and (i) early medical factors, (ii) neurobehavioral functioning and feeding at term equivalent age, (iii) cerebral structure and (iv) maternal mental health were investigated using regression.
Results:
Eighteen (23%) children had feeding problems at age 2 years. Feeding problems were associated with early hypotonia (p = 0.03; β = 0.29) and lower socio-economic status (p = 0.046; β = -0.22). No associations were observed between early medical factors, early feeding performance, cerebral structure alterations or maternal well-being and feeding outcome.
Conclusion:
Early hypotonia may disrupt the development of oral-motor skills. Hypotonia and poor feeding also may share a common aetiology. Associations with lower socio-economic status highlight the potential influence of family background factors in feeding problems in the preterm infant.
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