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Related Concept Videos

Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...

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Related Experiment Video

Updated: May 8, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

Screening for dementia--is it a no brainer?

C Fox1, L Lafortune, M Boustani

  • 1Department of Psychological Sciences, Faculty of Medicine and Health Sciences, Norwich Medical School, University of East Anglia, Norwich, UK.

International Journal of Clinical Practice
|August 20, 2013
PubMed
Summary
This summary is machine-generated.

Dementia affects millions globally, with numbers expected to double. Early diagnosis is crucial due to a lack of effective dementia treatments, driving research into predictive assessment tools and biomarkers.

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Area of Science:

  • Gerontology and Neurology
  • Public Health

Background:

  • Dementia is a growing societal concern, impacting millions worldwide.
  • Global dementia prevalence is projected to double every 20 years.
  • Current treatments do not significantly alter dementia's clinical course.

Purpose of the Study:

  • To address the increasing societal impact of dementia.
  • To highlight the importance of early dementia diagnosis.
  • To explore advancements in diagnostic tools and biomarkers.

Main Methods:

  • Review of current dementia prevalence data.
  • Analysis of research trends in diagnostic assessment.
  • Examination of biomarker research for dementia prediction.

Main Results:

  • Dementia prevalence is substantial and rising globally.
  • Research is focusing on early detection methods.
  • Biomarkers are being investigated for predictive diagnostic capabilities.

Conclusions:

  • Early diagnosis of dementia is a key focus area.
  • Advancements in assessment tools and biomarkers are critical.
  • Understanding the link between pathobiology and clinical presentation is emphasized.