Related Experiment Video
Updated: May 8, 2026

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
Published on: December 4, 2020
Recurrent acute otitis media in infants: analysis of risk factors
Mohamed Salah1, Mosaad Abdel-Aziz, Ahmed Al-Farok
1Department of Otolaryngology, Faculty of Medicine, Cairo University, Egypt.
Insights
Pacifier use, short breastfeeding, older age, winter, and upper respiratory infections are key risk factors for recurrent acute otitis media in infants. Adenoid hypertrophy and short breastfeeding also impact treatment success.
Area of Science:
- Pediatrics
- Otolaryngology
- Infectious Diseases
Background:
- Recurrent acute otitis media (RAOM) in infants leads to significant morbidity and parental distress.
- Identifying risk factors is crucial for managing RAOM and preventing treatment failures.
Purpose of the Study:
- To analyze risk factors for RAOM in infants.
- To determine the impact of these factors on treatment failure.
Main Methods:
- Retrospective study of 340 infants diagnosed with RAOM.
- Data collected from medical charts, analyzing factors like age, breastfeeding duration, pacifier use, URTI, and adenoid hypertrophy.
Main Results:
- Identified risk factors for RAOM include pacifier use, short breastfeeding duration, older infant age, winter season, URTI, and adenoid hypertrophy.
- Treatment failure was associated with adenoid hypertrophy, short breastfeeding, and older infant age.
Conclusions:
- Pacifier use, limited breastfeeding, older infant age, winter seasonality, URTI, and adenoid hypertrophy are significant contributors to RAOM.
- Adenoid hypertrophy and short breastfeeding duration are linked to treatment failure, highlighting areas for improved management.
Objective:
Recurrence acute otitis media (RAOM) may cause a considerable morbidity and a great parental concern. The aim of this study was to analyze the risk factors that are likely to be responsible for RAOM in infants, and their impact on treatment failure.
Methods:
A retrospective study on 340 infants with RAOM was conducted. Data were collected from hospital charts. A 10 days course of amoxicillin/clavulanate was used for treatment of recurrence, while surgical management in the form of adenoidectomy and/or myringotomy was reserved for patients with persistent disease. We analyzed various risk factors that may affect the prognosis of RAOM, including: age, prematurity, upper respiratory tract infections (URTI), duration of breastfeeding, use of pacifiers, parental smoking, seasonality, the presence of siblings (family size), gender, adenoid hypertrophy, allergy, and craniofacial abnormalities.
Results:
Use of pacifiers, short duration of breastfeeding, older infantile age, winter season, URTI and presence of adenoid hypertrophy were identified as risk factors for RAOM. Treatment failure may be due to adenoid hypertrophy, short duration of breastfeeding and it is more common in older age infants. We did not find a significant association between RAOM and gender, prematurity, exposure to passive smoking, the presence of siblings, allergy, craniofacial abnormalities.
Conclusions:
Factors that may cause recurrence of the disease in infant population are use of pacifiers, short duration of breastfeeding, older infantile age, winter season, upper respiratory tract infections and adenoid hypertrophy. Also, treatment failure may be caused by adenoid hypertrophy and short duration of breastfeeding. Good understanding of these factors may help to decrease the recurrence rate and to improve the treatment of the disease.
Related Concept Videos
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia I: Introduction
Tonsillitis I: Introduction
Etiology
Three primary contributing factors have been identified.
Tonsillitis II: Management
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
