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Updated: May 8, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Radiographic manifestations of transfusion-related acute lung injury
Carolina Carcano1, Ndubuisi Okafor, Felipe Martinez
1Radiology Department, Cleveland Clinic Florida, Weston, FL 33331.
Objective:
The purpose of this article is to describe the clinical symptoms and illustrate the radiological manifestations of transfusion-related acute lung injury (TRALI) as the condition develops. We mention those findings that aid the discrimination from transfusion-associated cardiac overload. We will also point some of the characteristics that increase the risk of TRALI.
Conclusion:
TRALI generally occurs within 1 to 2 h of the start of a blood transfusion. Though the radiographic features of TRALI are nonspecific, the diagnosis is established using clinical and radiological parameters. The diagnosis warrants a high index of suspicion as well as knowledge of its risk factors. There are no specific treatments; the best chance of survival in TRALI is with early diagnosis and prevention.
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