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Published on: August 11, 2023
Cerebral embolic stroke after disappearing takotsubo cardiomyopathy
Kosuke Matsuzono1, Yoshio Ikeda, Shoko Deguchi
1Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and pharmaceutical science, Okayama, Japan.
Insights
Takotsubo cardiomyopathy can cause stroke due to blood clots. This case shows that stroke risk persists even after heart function recovers, highlighting the importance of timing for anticoagulation therapy in takotsubo cardiomyopathy patients.
Area of Science:
- Cardiology
- Neurology
- Thrombosis
Background:
- Takotsubo cardiomyopathy (TTC) is a form of non-ischemic heart failure.
- Intracardiac thrombosis in TTC can lead to embolic stroke.
- The temporal relationship between TTC resolution and embolic events is not well-established.
Observation:
- A 71-year-old woman with TTC developed a cerebral embolic stroke.
- The stroke occurred after the recovery of cardiac wall motion abnormalities.
- The patient was treated with anticoagulation therapy.
Findings:
- Cardiogenic embolism can occur during the recovery phase of TTC.
- The timing of embolism relative to cardiac recovery is a critical factor.
- Anticoagulation therapy is a potential treatment modality.
Implications:
- Clinicians should consider the risk of stroke even after TTC resolution.
- Monitoring and timely anticoagulation are crucial for patients with TTC.
- Further research is needed to define optimal management strategies for TTC-associated stroke.
Abstract:
Takotsubo cardiomyopathy can induce cerebral embolic stroke because of intracardiac thrombosis, but the timing of cardiogenic embolism relating to takotsubo cardiomyopathy has not been well described. We evaluated a 71-year-old woman with takotsubo cardiomyopathy, who developed cardiogenic cerebral embolism after recovery of cardiac wall motion. Nevertheless, we treated her with anticoagulation therapy. The present clinical observation suggests that attention should be paid to the timing when takotsubo cardiomyopathy resolves against risk of cardiogenic cerebral embolism.
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